Observational Study to Evaluate the Real-Life Effectiveness of Benepali Following Transition From Enbrel

Key Inclusion Criteria:

• Must have been diagnosed with either rheumatoid arthritis or axial spondyloarthritis, according to local practice
• Transition from Enbrel to Benepali at the physician's (Investigator's) discretion prior to enrolment into the study
• Must have been treated with the same dose of Enbrel for at least 6 months prior to transition to Benepali and have at least 1 efficacy data value including but not restricted to DAS-28 or BASDAI during that period
• Must have a stable disease throughout the 2 month prior to enrolment based on the Investigator's judgement
• Women of childbearing potential should be advised to use appropriate contraception to avoid becoming pregnant during Benepali therapy and for three weeks after discontinuation of therapy

Key Exclusion Criteria:

• Have any medical conditions that precludes administration of Benepali according to Summary of Product Characteristics (SmPC), such as the following:
• Hypersensitivity to the Benepali active substance, or to any of the associated excipients
• Sepsis, or risk of sepsis
• Active clinically significant local or chronic viral, bacterial or fungal infection, or any major episode of infection requiring hospitalization or treatment with parenteral anti-infectives within 2 months prior to enrollment
• Show any clinical sign or medical condition not allowing for treatment continuation (of etanercept) in the judgment of the Investigator
• Treatment with another biologic agent
• Are currently receiving or have previously received any therapies that would preclude administration of Benepali, such as the following:
• Immunizations with live or live-attenuated vaccines within the last 6 months prior to transition point and throughout the observation period
• Treatment with investigational agents within the last 6 months prior to transition point and during the period of observation.
• Any other unspecified reasons that would, in the opinion of the Investigator, make the patient unsuitable for enrollment.

NOTE: Other protocol defined Inclusion/Exclusion criteria may apply.