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Completed

NCT Number: NCT05942976

Enthesis Differences in Rheumatoid Arthritis and Axial Spondyloarthropathy

The aim of this study is to investigate the sonographic differences in entheses in patients with Rheumatoid arthritis and Axial Spondyloarthropathy.

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Key information

Conditions

Axial Spondyloarthritis Ankylosis Arthritis Arthritis, Rheumatoid Autoimmune Diseases Bone Diseases Connective Tissue Diseases Enthesitis Enthesopathy Immune System Diseases Joint Diseases Muscular Diseases Musculoskeletal Diseases Rheumatic Diseases Rheumatoid Arthritis Skin and Connective Tissue Diseases Spinal Diseases Spondylarthritis Spondylarthropathies Spondylitis Tendinopathy Tendon Injuries Wounds and Injuries

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Istanbul Training and Resarch Hospital

Istanbul, Turkey (Türkiye)

About this study

After recording the demographic data of the patients; 5 enthesis regions 5 enthesis sites were evaluated bilaterally as ''tricipital tendon (TT), quadricipital tendon (QT), proximal patellar tendon (PPT), distal patellar tendon (DPT), achilles tendon (AT)'' will be sonographically evaluated and the presence of hypoechogenicity , tendon thickness increase, power Doppler activity, erosion, presence of entezophyte/calcification will be investigated. The differences between the groups will then be compared.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Rheumatoid arthritis patients identified according to the 2010 American College of Rheumatology /Europan Leage Against Rheumatism classification criteria,
  • axial Spondyloarthrtis patients identified according to the Assessment of Spondyloarthritis classification criteria
  • healthy controls with no history of rheumatic diseases.

Exclusion criteria

  • history of limb trauma and surgery in the last 3 months,
  • metabolic disease (diabetes mellitus, hypothyroidism),
  • malignant neoplasm,
  • limitation of range of motion in the extremity,
  • those who have received corticosteroid injections in the last 3 months,
  • uncontrollable fibromyalgia.

Treatment and study plan

ultrasound

Other

10 enthesis areas will be evaluated in 20 minutes with ultrasound.

Primary outcomes

  1. Ultrasound enthesis differences between the groups

    Time frame: 2 months

    triceps tendon, quadriceps tendon, proximal patellar tendon, distal patellar tendon and achilles tendons enthesitis scores differences between the groups

  2. The relationship between ultrasound findings and disease parameters

    Time frame: 2 months

    The relationship between triceps tendon, quadriceps tendon, proximal patellar tendon, distal patellar tendon and achilles tendons enthesitis scores and Clinical disease activity index and BASDAI

Sponsors and collaborators

Lead sponsor

Istanbul Training and Research Hospital

Other Gov

Registry information

Official study title

Ultrasonographic Differences in Entheses in Rheumatoid Arthritis and Axial Spondyloarthropathy Patients

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Jul 12, 2023
Registry last updated
Sep 6, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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