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OpenTrials
Completed

NCT Number: NCT00599508

Nutritional Supplementation in Cognitive Aging

To evaluate the effect of supplemented berry fruit juice and whole fruit berry powder on memory performance and brain function in older adults

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Key information

Conditions

Cognitive Aging

Age range

66 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Cincinnati

Cincinnati, Ohio, 45267-0559, United States

About this study

Randomized trials involving daily supplementation with berry fruits in older adults with early memory changes. The berry products include Concord grape juice, blueberry juice, and whole fruit blueberry powder. Supplementation periods are 12 and 16 weeks, depending on berry product. The Aims of the studies are to assess effects on cognitive performance and in a subset of participants, in brain activity.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Mild Cognitive Impairment

Exclusion criteria

  • Diabetes
  • Weight of under 100 or over 210 pounds
  • Chronic use of pain medication

Treatment and study plan

Concord grape juice

Dietary Supplement

Several ounces Concord grape juice administered 3 times a day for 12 or 16 weeks. Specific dosage determined by participant's weight.

Other names: Welch's Concord Grape Juice

Placebo Juice

Dietary Supplement

several ounces placebo juice consumed three times a day for 12 or 16 weeks; dosage determined according to participant's weight

blueberry juice

Dietary Supplement

wild blueberry juice administered daily for 12 weeks, dosage determined according to participant's weight

whole fruit blueberry powder

Dietary Supplement

whole fruit, freeze dried blueberry powder derived from a blend of cultivated blueberries administered daily for 16 weeks

berry placebo powder

Dietary Supplement

berry placebo powder administered daily for 16 weeks

Primary outcomes

  1. memory performance

    Time frame: at the end of the intervention

Secondary outcomes

  1. cortisol

    Time frame: at the end of the intervention

Sponsors and collaborators

Lead sponsor

University of Cincinnati

Other

Collaborators

  • U.S. Highbush Blueberry Council
  • Welch Foods Incorporated

Registry information

Important dates

Study start
2006
Primary completion
2015
Study completion
2015
First posted
Jan 23, 2008
Registry last updated
Oct 10, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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