West German Heart and Vascular Centre Essen, University Hospital Essen
Essen, Germany
NCT Number: NCT07512310
This study evaluates how different non-invasive and invasive measurements reflect left ventricular filling pressure, an important indicator of cardiac function. Elevated filling pressure is associated with symptoms such as shortness of breath and plays a central role in the diagnosis and management of heart failure and pulmonary hypertension.
In clinical practice, filling pressure can be estimated using echocardiography or measured during cardiac catheterisation. However, the relationships between these measurements and their ability to accurately reflect true filling pressure are not fully understood.
This retrospective study includes patients who underwent cardiac catheterisation with invasive haemodynamic assessment and temporally related echocardiographic evaluation as part of routine clinical care. The aim is to improve understanding of how different measurements relate to each other and to identify which parameters best reflect elevated filling pressure.
The results are expected to support more accurate interpretation of haemodynamic measurements and improve clinical decision-making, particularly regarding the use of non-invasive versus invasive assessment.
Looking for future studies?
Notify Me18 year and older
All sexes
Observational
Essen, Germany
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: At the time of cardiac catheterisation (baseline)
Assessment of the ability of non-invasive and invasive surrogate parameters to identify elevated left ventricular filling pressure, with simultaneously obtained invasive left ventricular end-diastolic pressure serving as the reference standard
University Hospital, Essen
Other
NIPRESS: Non-Invasive and Invasive Pressure Evaluation and Stratification Study
Acronym: NIPRESS
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT00391846
Cardiovascular Diseases, Heart Diseases
Alvesta, Sweden
View Trial DetailsNCT03629340
Cardiovascular Diseases, Heart Diseases
San Francisco, California, United States
View Trial DetailsNCT06671171
Arterial Occlusive Diseases, Arteriosclerosis
Hong Kong
View Trial DetailsNCT05996562
Cardiovascular Diseases, Heart Diseases
Lisbon, Portugal
View Trial Details