Neuroplastic Alterations of the Motor Cortex by Caffeine

Inclusion criteria

• Male and female healthy participants between the ages of 18-45.
• Right-handed (Oldfield 1971).
• Free willing participation and written, informed consent of all subjects obtained prior to the start of the study.
• Participant's weight is above 60 kg

Exclusion criteria

• Age < 18 or > 45 years old;
• Left hand dominant;
• Evidence of a chronic disease or history with a disorder of the nervous system
• History of epileptic seizures;
• Pacemaker or deep brain stimulation;
• Metal implants in the head region (metal used in the head region, for example, clips after the operation of an intracerebral aneurysm (vessel sacking in the region of the brain vessels), implantation of an artificial auditory canal);
• Cerebral trauma with loss of consciousness in prehistory;
• Existence of a serious internal (internal organs) or psychiatric (mental illness)
• Alcohol, medication or drug addiction;
• Receptive or global aphasia (disturbance of speech comprehension or additionally of speech);
• Participation in another scientific or clinical study within the last 4 weeks;
• Pregnancy
• Breastfeeding
• Intolerance to caffeine or coffee products
• Participant who has abnormal heart activity from an electrocardiography (ECG) finding
• Weight is less than 60 kg