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Completed

NCT Number: NCT05905107

Neurodynamic Sequencing in Patients With Carpal Tunnel Syndrome

Carpal tunnel syndrome is a compressive neuropathy of median nerve in the fascial tunnel at wrist which causes pain, numbness ,and tingling in the extremities. Common treatment options used in the treatment of carpal tunnel syndrome are conservative and surgical treatment option is better, this question is still a topic requiring more and more clinical trials. Neuromobilisation described by Butler is one of the treatment options which are used in the treatment of carpal tunnel syndrome in conjunction with other conservative measures.

This proposed study will find out the effectiveness of Neuromobilisation in treatment of carpal tunnel syndrome. As there is very little evidence available which Neuromobilisation technique is effective and what are the types of patients which can get benefit from this technique. This study will find out the effect of Neuromobilisation in patients suffering from carpal tunnel syndrome of non traumatic origin. This is a randomized clinical trial. Target population is patients suffering from carpal tunnel syndrome of non-traumatic origin. Data will be collected from District Headquarter Hospital Faisalabad. This study will include 56 participants according to the selection criteria. The participants will be randomly divided into two groups through sealed opaque envelop method.

Group A will recruit 28 patients which fulfill the inclusion criteria. These patients will be treated by nerve sequencing proximal to distal in 3 sets of 15 repetitions in one session on alternate days for 4 weeks. Group B will recruit 28 patients which fulfill the inclusion criteria. These patients will be treated by nerve sequencing distal to proximal in 3 sets of 10 repetitions in one session for 4 weeks. The Statistical analysis will be performed through SPSS Software 21.

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Key information

Age range

25 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

District Headquarters Hospital

Faisalābad, Punjab Province, 38000, Pakistan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients positive for provocative test ( Phalen's test, Wrist decompression test and tinnel test).

Exclusion criteria

  • Inflammation around the wrist
  • Tumor around the wrist
  • Rheumatoid Arthritis
  • Osteoporosis
  • Joint Hypermobility

Treatment and study plan

Neurodynamic Slider Technique from Proximal to Distal

Other

Neurodynamic Slider Technique from proximal to distal at wrist, elbow and neck

Neurodynamic Slider Technique from Distal to Proximal

Other

Neurodynamic Slider Technique from proximal to distal at wrist, elbow and neck

Primary outcomes

  1. Pain at wrist joint

    Time frame: 4 weeks

    Pain will be assessed by using Numerical Pain Rating Scale Pain will be assessed by using Numerical Pain Rating Scale

  2. Wrist Range of Movement at wrist joint

    Time frame: 4 weeks

    Range of motion will be assessed by using Goniometer

  3. Functional Ability at wrist joint

    Time frame: 4 weeks

    Functional Ability will be assessed by using Boston Carpal tunnel syndrome

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Official study title

Effects of Neurodynamic Sequencing on Pain, Wrist Range of Movement and Functional Disability in Patients With Carpal Tunnel Syndrome

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Jun 15, 2023
Registry last updated
Nov 20, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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