Skip to main content
OpenTrials
Completed

NCT Number: NCT07724717

Effects of Whole Wrist Versus Specific Carpal Bone Mobilization in the Patients of Carpel Tunnel Syndrome

The study was conducted to compare the effectiveness of Whole Wrist Mobilization versus Specific Carpal Bone Mobilization in reducing symptoms and improving function in patients with Carpal Tunnel Syndrome (CTS).

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Carpal Tunnel Syndrome Cumulative Trauma Disorders Median Neuropathy Mononeuropathies Nerve Compression Syndromes Nervous System Diseases Neuromuscular Diseases Peripheral Nervous System Diseases Sprains and Strains Wounds and Injuries

Age range

30 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Riphah Rehabilitation Clinic, Lahore, Punjab Province, Pakistan

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Participants aged 30 to 60 years old
  • Both male and female participants
  • CTS for at least 2 months
  • Pain levels on the Numeric Pain Rating Scale (NPRS) between 3 and 7
  • Limited range of motion and wrist pain
  • Patient with positive PHALEN and TINEL test

Exclusion criteria

  • Prior traumatic injury of wrist
  • History of wrist surgery
  • Diagnoses of polyneuropathy, cervical radiculopathy, myelopathy, inflammatory arthritis, diabetes, thyroid disease
  • Presence of abnormal sensation in the wrist region
  • Hemorrhagic tendency and/or current anticoagulation treatment
  • History of whiplash injury

Treatment and study plan

Specific Bone Mobilization

Other

Scaphoid Mobilization: The therapist applied anterior-posterior mobilization on the scaphoid while the patient's wrist was in slight flexion. It was held for 5 seconds and repeated for 10 repetitions.

Lunate Mobilization: The therapist performed lateral and medial mobilization of the lunate while stabilizing the forearm. It was held for 5 seconds and repeated for 10 repetitions.

Triquetrum Mobilization: With the wrist in a neutral position, the therapist applied gentle mobilization to the triquetrum. It was held for 5 seconds and repeated for 10 repetitions.

Whole Wrist Mobilization

Other

Distal Radioulnar Joint Mobilization: To perform mobilizations at the distal radioulnar joint, the therapist stabilized the patient's hand and radiocarpal region, then provided anteroposterior glide and medial and lateral rotary joint play movements of the distal ulna.

Radiocarpal Joint - Dorsal Palmar Glide:

The mobilization involved moving the row of carpal bones either dorsally to promote wrist extension or palmary to promote wrist flexion.

Radiocarpal Joint - Ulnar and Radial Glide: Ulnar glide was performed to increase radial deviation, while radial glide was performed to increase ulnar deviation of the wrist joint.

Mid-Carpal Joint Mobilization: The mobilization involved moving the row of carpal bones either dorsally to promote wrist extension or palmary to promote wrist flexion.

Standardized Physiotherapy Treatment

Other

Hot Pack: A hot pack was applied to the wrist and forearm for 10 minutes to help relax the muscles and improve circulation around the carpal tunnel.

Transcutaneous Electrical Nerve Stimulation: TENS was applied with a frequency of 2 Hz and a pulse duration of 200 µs for 10 minutes over the wrist area to reduce pain and discomfort.

Wrist Flexion and Extension: With the arm supported, the patient actively flexed and extended the wrist through a full range of motion. This was repeated for 10 repetitions.

Radial and Ulnar Deviation: With the arm supported, the patient actively moved the wrist side to side (radially and ulnarly).

Wrist Circles: The patient performed circular motions with the wrist in both clockwise and counterclockwise directions. This was repeated for 10 repetitions.

Wrist Flexor Stretch:

The arm was extended in front with the palm facing up, and the fingers were gently pulled back to stretch the wrist flexors. The stretch was held for 30 seconds and repeated 3 times.

Primary outcomes

  1. Numeric Pain Rating Scale

    Time frame: From enrollment to the end of treatment at 4 weeks

    The Numeric Pain Rating Scale (NPRS) was used to assess pain intensity, with participants rating their pain from 0 (no pain) to 10 (worst possible pain). It provided a quantitative measure to track pain changes over time.

  2. Boston Carpal Tunnel Questionnaire

    Time frame: From enrollment to the end of treatment at 4 weeks

    The Boston Carpal Tunnel Questionnaire (BCTQ) is a recommended tool for assessing the functional status and severity of symptoms in CTS patients.

  3. ROM Wrist Flexion

    Time frame: From enrollment to the end of treatment at 4 weeks

    Changes in wrist flexion ROM at baseline and 4th week of intervention was measured using goniometer.

  4. ROM Wrist Extension

    Time frame: From enrollment to the end of treatment at 4 weeks

    Changes in wrist extension ROM at baseline and 4th week of intervention was measured using goniometer.

  5. ROM Wrist Radial Deviation

    Time frame: From enrollment to the end of treatment at 4 weeks

    Changes in wrist radial deviation ROM at baseline and 4th week of intervention was measured using goniometer.

  6. ROM Wrist Ulnar Deviation

    Time frame: From enrollment to the end of treatment at 4 weeks

    Changes in wrist ulnar deviation ROM at baseline and 4th week of intervention was measured using goniometer.

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jul 24, 2026
Registry last updated
Jul 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.