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OpenTrials
Completed

NCT Number: NCT07415174

Neck Exercises After Thyroid Surgery

Postoperative neck pain is common after thyroidectomy and may impair early recovery. This prospective randomized controlled study aimed to evaluate the effects of postoperative neck range-of-motion (ROM) and isometric strengthening exercises on neck pain and early-stage quality of life in patients undergoing thyroidectomy. Between November 2024 and April 2025, 93 patients who underwent thyroidectomy were enrolled. Surgical indications included multinodular goiter, Graves' disease, and fine-needle aspiration biopsy results classified as Bethesda categories III-VI. Patients were randomized into an intervention group (n = 48) and a control group (n = 45). Patients in the intervention group performed cervical ROM and isometric strengthening exercises from postoperative day 1 to day 10, while the control group received standard postoperative care without a structured exercise program. Both groups were evaluated on postoperative days 1 and 10. Pain severity was assessed using the Visual Analog Scale (VAS), and quality of life was assessed using the Neck Pain, Discomfort, and Early-Stage Quality of Life Questionnaire (NPDEPQ).

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Department of General Surgery

Istanbul, 34096, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults aged 18 years or older
  • Patients who underwent thyroidectomy for multinodular goiter, Graves' disease, or fine-needle aspiration biopsy results classified as Bethesda categories III, IV, V, or VI
  • Ability to understand and comply with the study protocol
  • Provision of written informed consent

Exclusion criteria

  • Age younger than 18 years
  • History of previous neck surgery
  • Cervical disc herniation
  • Parathyroidectomy
  • Hashimoto's thyroiditis
  • Refusal to provide written informed consent

Treatment and study plan

Postoperative Neck Exercise Program

Other

A structured postoperative program including neck range-of-motion and isometric strengthening exercises, initiated on postoperative day 1 and performed for 10 consecutive days, three times daily.

Primary outcomes

  1. Postoperative Neck Pain

    Time frame: Postoperative day 1 and postoperative day 10

    Postoperative neck pain was assessed using the Visual Analog Scale (VAS), where scores range from 0 (no pain) to 10 (worst imaginable pain). Assessments were performed on postoperative day 1 before discharge and on postoperative day 10 during follow-up by a blinded outcome assessor.

Secondary outcomes

  1. Neck Discomfort and Early-Stage Quality of Life

    Time frame: Postoperative day 1 and postoperative day 10

    Neck discomfort and early-stage quality of life were evaluated using the Neck Pain, Discomfort, and Early-Stage Quality of Life Questionnaire (NPDEPQ). Assessments were conducted on postoperative day 1 and postoperative day 10 by a blinded outcome assessor.

Sponsors and collaborators

Lead sponsor

Istanbul University - Cerrahpasa

Other

Registry information

Official study title

Effect of Postoperative Neck Range-of-Motion and Isometric Strengthening Exercises on Neck Pain and Early-Stage Quality of Life After Thyroidectomy

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Feb 17, 2026
Registry last updated
Feb 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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