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OpenTrials
Completed

NCT Number: NCT07522983

RECURRENT LARYNGEAL INJURY WHILE USING LIGASURE Versus CONVENTIONAL KNOT TYING IN TOTAL THYROIDECTOMY

To compare the frequency of recurrent laryngeal injury during total thyroidectomy when utilizing the LigaSure technique against conventional knot tying.

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Key information

Conditions

Thyroidectomy Endocrine System Diseases Thyroid Diseases

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Gulab Devi Hospital Ferozpur Road Lahore

Lahore, Punjab Province, 54600, Pakistan

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Aged: 18 to 60 years
  • Both Gender
  • Patients undergoing total thyroidectomy
  • Normal IDL
  • No Hoarseness of voice

Exclusion criteria

  • Patients requiring re-operation, including completion thyroidectomy.
  • Patients undergoing concurrent procedures such as cervical lymphadenectomy or parathyroidectomy.
  • Patient having previous neck surgery
  • Patient having neck radiation
  • Thyroidectomy for thyroid malignancy

Treatment and study plan

tie and knot

Procedure

patients designated for total thyroidectomy with tie and knot hemostasis

Other names: Group conventional vessel sealing

LigaSure

Procedure

Ligasure for hemostasis

Other names: Ligasure vessel sealing

Primary outcomes

  1. Recurrent laryngeal nerve injury

    Time frame: 3 days

    Patients will be admitted to the hospital ward and assessed for recurrent laryngeal injury as per the operational definition during their stay.

Sponsors and collaborators

Lead sponsor

Gulab Devi Hospital

Other

Registry information

Official study title

INCIDENCE OF RECURRENT LARYNGEAL INJURY WHILE USING LIGASURE IN TOTAL THYROIDECTOMY AS COMPARED TO CONVENTIONAL KNOT TYING

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Apr 13, 2026
Registry last updated
Apr 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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