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Completed

NCT Number: NCT01997970

NEAT - Prevention and Treatment of Overweight and Obesity.

This study will investigate the effect on Non-exercise Activity Thermogenesis (NEAT) when implementing active workstation at offices compared to conventional office work. The primary hypothesis is that this implementation will lead to a significant increase in time spent walking per day.

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Key information

Conditions

Overweight Body Weight Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

40 year–67 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Umeå University

Umeå, Sweden

About this study

NEAT consists of the energy expenditure of the physical activities that are non sporting-like and that we perform in our everyday life, such as walking, cleaning, shoveling snow etc. Which occupation we have play a big role in how much we are able to active our NEAT during our days and those who have more active jobs can expend up to 1500kcal more per day than those with sedentary jobs.

This study aims to try and increase NEAT at offices where sedentary time often is high. Participants will be randomized to either an intervention group or to a control group. Participants in the control group will continue to work at their regular desk, but will receive an individual health talk in the beginning of the study where diet and physical activity recommendations will be discussed.Participants in the intervention group will receive the same individual health talk and a treadmill desk, which they will use for 12 months at self-selected speed. They will be recommended to walk on the treadmill for at least 1 hour per day.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Office workers with mainly sedentary tasks
  • BMI 25-40

Exclusion criteria

  • Severe depression and/or anxiety
  • Exhaustion disorder
  • Diabetes Mellitus
  • Severe cardiovascular disease
  • Severe kidney disease
  • Musculoskeletal disorders that prohibit walking on a treadmill
  • Contraindications for physical activity
  • Thyroidea illness
  • Pregnancy

For fMRI-study, additional exclusion criteria are:

  • Implanted metal- or electrical devices
  • Pregnancy
  • Extraneous metal pieces in the body

Treatment and study plan

Treadmill workstation

Behavioral

The intervention group will receive a treadmill workstation for 12 months. They will use this at self-selected speed and will be recommended to use this for at least 1 hour per day. Participants in the control group will continue with conventional office work at their regular desk. Participants in the intervention group will receive four boosting e-mails during the study period, in which they will be encouraged to use the treadmill.

Health talk

Behavioral

Participants in both groups will receive a health talk with recommendations about diet and physical activity habits.

Primary outcomes

  1. Change from baseline in physical activity and sedentariness at 12 months

    Time frame: Baseline, 12 months

    Measured with an accelerometer (ActiGraph) and an inclinometer (ActivPAL).

Secondary outcomes

  1. Change from baseline in metabolism at 12 months

    Time frame: Baseline, 12 months

    Metabolism: 2h glucose tolerance test. lipids, Hb1Ac

  2. Change from baseline in anthropometrics at 12 months

    Time frame: Baseline, 12 months

    Length, height, weight, waist circumference, hip circumference, sagittal height, pulse, blood pressure.

  3. Change from baseline in body composition at 12 months

    Time frame: Baseline, 12 months

    Measured with Dual X-Ray Absorptiometry (DXA)

  4. Change from baseline in musculoskeletal pain at 12 months

    Time frame: Baseline, 12 months

    Measured with the Chronic Pain Grade Questionnaire

  5. Change from baseline in stress at 12 months

    Time frame: Baseline, 12 months

    Measured by assessing cortisol levels in the saliva at 4 time points during one day. Also measured with the stress- and energy scale.

  6. Change from baseline in depression/anxiety at 12 months

    Time frame: Baseline, 12 months

    Measured with the Hospital Anxiety and Depression Scale.

  7. Change from baseline in Quality of Life at 12 months

    Time frame: Baseline, 12 months

    Measured with 2 questions from the SF-36.

  8. Change from baseline in cognitive Function and functional brain response at 12 months

    Time frame: Baseline, 12 months

    Measured with a cognitive test battery and functional MRI (fMRI). Levels of Brain-Derived Neurotrophic Factor (BDNF) is measured in the plasma.

  9. Qualitative interview study

    Time frame: 12 months

    Participants will be interviewed about experiences from being part of the study and about attitudes and factors that influences them to be physically active.

Sponsors and collaborators

Lead sponsor

Umeå University

Other

Registry information

Official study title

Non-exercise Activity Thermogenesis (NEAT) - Prevention and Treatment of Overweight and Obesity

Acronym: InphactUm

Important dates

Study start
2014
Primary completion
2015
Study completion
2015
First posted
Nov 28, 2013
Registry last updated
May 12, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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