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NCT Number: NCT07643246

National Study on the Prevalence of Catheter-Related Venous Thrombosis

The aim is to determine the prevalence of catheter-related thrombosis (CRT) in hospitalized patients carrying PICC, FICC, CICC, and midline catheters through a multicenter, standardized prevalence study. To achieve this, a cross-sectional study with prospective data collection will be conducted, including, through consecutive sampling to minimize selection bias, all hospitalized patients over 18 years of age from both general wards and critical care units who have had one of these catheters in place for at least 7 days. During data collection, an ultrasound examination of the catheter insertion site will be performed in order to rule out the presence of thrombotic complications.

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Key information

Conditions

Thrombosis Cardiovascular Diseases Embolism and Thrombosis Vascular Diseases Venous Catheterization

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All hospitalized patients aged ≥18 years from all hospital wards, including critical care units, who are carriers of a midline, FICC, PICC, or CICC catheter with a dwell time of at least 7 days will be included.

Exclusion criteria

  • Patients who do not provide informed consent for the ultrasound assessment.

Treatment and study plan

Primary outcomes

  1. Overall prevalence of catheter-related thrombosis

    Time frame: From the beginning of the cutoff to the end of the cutoff at 4 weeks

    Number of patients with CRT / total number of patients evaluated) × 100

Secondary outcomes

  1. Symptomatic CRT

    Time frame: From the beginning of the cutoff to the end of the cutoff at 4 weeks

    (Number of CRT cases with ≥1 clinical sign / total number of CRT cases) × 100

  2. Asymptomatic CRT

    Time frame: From the beginning of the cutoff to the end of the cutoff at 4 weeks

    (Number of CRT cases without clinical signs / total number of CRT cases) × 100

  3. Superficial CRT

    Time frame: From the beginning of the cutoff to the end of the cutoff at 4 weeks

    Number of superficial CRT cases / total number of CRT cases) × 100

  4. Deep CRT

    Time frame: From the beginning of the cutoff to the end of the cutoff at 4 weeks

    Number of deep CRT cases / total number of CRT cases) × 100

  5. Prevalence by responsible service

    Time frame: From the beginning of the cutoff to the end of the cutoff at 4 weeks

    (Number of CRT cases in each service category / total number of patients evaluated in that service) × 100

  6. Time from implantation to CRT diagnosis

    Time frame: From the beginning of the cutoff to the end of the cutoff at 4 weeks

    Mean, SD, median, and IQR (interquartile range) of elapsed days

  7. Distribution by implanting operator

    Time frame: From the beginning of the cutoff to the end of the cutoff at 4 weeks

    Number of CRT cases by implanting operator / total number of CRT cases × 100

Sponsors and collaborators

Lead sponsor

Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta

Other

Collaborators

  • Althaia Xarxa Assistencial Universitària de Manresa
  • Hospital del Mar Research Institute (IMIM)

Registry information

Acronym: TROMBO

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jun 11, 2026
Registry last updated
Jun 11, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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