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OpenTrials
Completed

NCT Number: NCT07180641

National Registry of Hepatic Metastases From Non-Colorectal Cancer"

The investigators designed this observational, retrospective, multicenter study including all patients who underwent surgery for non-colorectal liver metastases between January 2010 and December 2022, with the aim of establishing a series of recommendations for the treatment of liver metastases from various extrahepatic primary tumors

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Key information

Conditions

Non-colorectal Liver Metastasis Hepatectomy Liver Metastases Liver Metastasis Liver Resection Non-colorectal Liver Metastases Non-neuroendocrine Liver Metastases Non-neuroendocrine Liver Metastasis

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients scheduled for liver surgery due to non-colorectal liver metastases, regardless of the primary tumor origin, via open or minimally invasive approach

Exclusion criteria

  • Patients undergoing surgery for colorectal liver metastases, emergency surgical interventions and patients younger than 18 years old.

Treatment and study plan

Primary outcomes

  1. Overall Survival

    Time frame: 5 years from liver resection

    Time from the date of liver resection for non-colorectal metastases to death from any cause. Survival will be assessed for up to 5 years postoperatively

  2. Progression-Free Survival

    Time frame: 5 years from surgery

    Time from the date of liver resection for non-colorectal metastases to the date of documented disease progression or death from any cause, whichever occurs first. Patients without progression or death will be censored at the last follow-up

Secondary outcomes

  1. Postoperative Morbidity Rate

    Time frame: 90 days from surgery

    Incidence of any postoperative complications occurring within 90 days after liver resection, including but not limited to infections, bleeding, bile leaks, and other surgical complications, classified according to standard criteria.

  2. Postoperative Mortality Rate

    Time frame: 90 days from surgery

    Proportion of patients who die from any cause within 90 days following liver resection surgery.

  3. Recurrence Pattern

    Time frame: Up to 5 years from liver resection

    Distribution and characterization of tumor recurrence (hepatic, extrahepatic, or both) after liver resection for non-colorectal metastases.

  4. Length of hospital stay

    Time frame: Perioperative/Periprocedural

    Number of days from surgery to discharge following liver resection

  5. R0 Resection Rate

    Time frame: At surgery

    Proportion of patients achieving complete microscopic liver tumor resection (R0) during liver resection

Sponsors and collaborators

Lead sponsor

Clinica Universidad de Navarra, Universidad de Navarra

Other

Registry information

Official study title

REGISTRO NACIONAL DE METÁSTASIS HEPÁTICAS DE CÁNCER NO COLORRECTAL

Acronym: REMENOCOR

Important dates

Study start
2010
Primary completion
2022
Study completion
2022
First posted
Sep 18, 2025
Registry last updated
Sep 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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