Skip to main content
OpenTrials
Completed

NCT Number: NCT07663929

Nasal Packing After Turbinoplasty

This study aims to to compare postoperative pain, patient comfort, and hemostatic safety among four non-absorbable nasal packing techniques following microdebrider-assisted inferior turbinoplasty (MAIT) and to identify the most effective low-cost packing option.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Nasal Packing

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Kafrelsheikh University Hospitals

Kafrelsheikh, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults aged 18-65 years.
  • Chronic bilateral nasal obstruction secondary to inferior turbinate hypertrophy.
  • Failure of conservative medical management for at least 3 months, including intranasal corticosteroids and oral antihistamines.
  • Positive decongestion test showing ≥30% improvement in anterior nasal cavity volume (V2-5 cm) on acoustic rhinometry after topical xylometazoline 0.5%, confirming predominantly mucosal rather than bony hypertrophy.
  • Inferior turbinate hypertrophy grade 3 or 4 according to the Camacho classification system.

Exclusion criteria

  • Significant nasal septal deviation affecting the nasal valve region.
  • Internal or external nasal valve collapse or stenosis.
  • Chronic rhinosinusitis with or without nasal polyposis.
  • Previous nasal or paranasal sinus surgery.
  • Coagulopathy or current anticoagulant therapy.
  • Uncontrolled systemic disease.
  • Pregnancy.
  • Active smoking.
  • Known allergic sensitization to any component of the nasal packing materials.

Treatment and study plan

Standard bilateral Merocel® nasal tampons packing after Microdebrider-assisted inferior turbinoplasty

Procedure

Standard bilateral Merocel® nasal tampons (Medtronic, USA) were inserted in their dry compressed form. Prior to insertion, each tampon was trimmed according to the dimensions of the patient's nasal cavity. Following contact with nasal secretions, the Merocel expanded to provide gentle and uniform pressure over the operative site.

A Merocel® tampon was enclosed within the finger portion of a sterile powder-free latex surgical glove after Microdebrider-assisted inferior turbinoplasty

Procedure

A Merocel® tampon was enclosed within the finger portion of a sterile powder-free latex surgical glove. The glove finger was then partially stripped to expose portions of the Merocel surface while retaining a thin latex interface, thereby preventing the glove from acting as a complete barrier and allowing contact between the Merocel and surrounding nasal secretions. This modification preserved the expansion and absorptive properties of the Merocel while creating a smoother, less adherent outer surface.

Merocel® tampons were coated with a thin uniform layer of topical broad-spectrum antibiotic ointment after microdebrider-assisted inferior turbinoplasty

Procedure

Merocel® tampons were coated with a thin uniform layer of topical broad-spectrum antibiotic ointment, such as fusidic acid 2% plus corticosteroids, prior to bilateral insertion. This modification was intended to provide localized antimicrobial coverage while preserving the hemostatic effect of the packing material.

terile ribbon gauze impregnated with white petroleum jelly (paraffin) after microdebrider-assisted inferior turbinoplasty

Procedure

Sterile ribbon gauze impregnated with white petroleum jelly (paraffin) was loosely packed into each nasal cavity in a layered accordion-like fashion, beginning at the nasal floor and progressing posteriorly. Packing density was standardized to achieve adequate hemostasis while avoiding excessive pressure on the nasal mucosa.

Primary outcomes

  1. Pain intensity

    Time frame: We assesed pain during first 48 hours postoperative.

    1.Pain intensity Assessed using the Visual Analogue Scale (VAS) (0 = no pain, 10 = worst imaginable pain)

  2. Bleeding after packing removal Assessed using a 4-point grading scale

    Time frame: We assesed bleeding immediately after nasal packing removal

    Grade 0 = no bleeding Grade 1 = oozing Grade 2 = continuous bleeding Grade 3 = bleeding requiring intervention or control in the operating room

Secondary outcomes

  1. Nasal fullness/pressure sensation

    Time frame: We assesed it during first 48 hours postoperative.

    Nasal fullness/pressure sensation Assessed using the Visual Analogue Scale (VAS; 0-10)

Sponsors and collaborators

Lead sponsor

Kafrelsheikh University

Other

Registry information

Official study title

Nasal Packing After Turbinoplasty, Is it Worthwhile? A Prospective Study ?

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jun 23, 2026
Registry last updated
Jun 23, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.