Skip to main content
OpenTrials
Completed

NCT Number: NCT04724304

Myocardial Blood Volume Measurement by Real-Time Myocardial Perfusion Echocardiography Correlates to Myocardial Compressibility by Cardiac Magnetic Resonance Imaging in Healthy Subjects

This study is being done to find out the normal amount of blood within the heart muscle and the variations in this blood flow between a cardiac MRI and TTE.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Healthy Adults

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Mayo clinic Rochester

Rochester, Minnesota, 55905, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥ 18 years.
  • Available for testing performed in Rochester, MN.
  • Willing to undergo both an echocardiogram with RTMPE and CMR.
  • Study subject providing consent.

Exclusion criteria

  • Adults < 18 years.
  • BMI <30 kg/m^2.
  • Hypertension.
  • Diabetes Mellitus.
  • Stroke.
  • Cardiomyopathy or structural heart disease.
  • Known coronary artery disease or history of myocardial infarction.
  • Contraindication to echo enhancement agent or gadolinium administration such as an allergy.
  • Renal GFR < 50 mL/mL.
  • Females who are pregnant.
  • Subject unwilling to consent.

Treatment and study plan

Real-Time Myocardial Echocardiography (RTMPE)

Diagnostic Test

Uses sound waves (ultrasound) to produce an images of the heart. During RTMPE a microbubble contrast agent is administered through an intravenous line (IV) to make the images of your heart clearer.

Magnetic resonance image (MRI)

Diagnostic Test

Imaging that focuses on the heart or blood vessels to assess size and function of the heart's chambers, thickness and movement of the walls of the heart, and blood flow in the blood vessels.

Primary outcomes

  1. Myocardial blood volume

    Time frame: Baseline

    Ratio in systole and diastole (MBVs/MBVd) by real-time myocardial perfusion echocardiography (RTMPE)

Sponsors and collaborators

Lead sponsor

Mayo Clinic

Other

Registry information

Important dates

Study start
2021
Primary completion
2021
Study completion
2021
First posted
Jan 26, 2021
Registry last updated
Apr 7, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.