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NCT Number: NCT05581680

Multimodal Quantified Analysis of Facial Movements: Comparison Between Pathological and Control Subjects

The facial palsy is a frequent disease with a lot of etiologies. It has variable severities with sometimes heavy functional repercussions and different recovery potentials. The proposed treatments are based on surgery, physiotherapy and botulinum toxin injections. However, when recovery is incomplete, acceptance is more difficult, with an impacted quality of life. Thanks to Motion Capture and Electromyography, a quantification of the facial mimicry is now possible with a great precision. In addition with the quantification of the facial mimicry, eye-tracking, wich is widely used in the marketing field, but it also finds medical applications including head and neck lesions and facial palsy in particular, will be used to evaluate the visio of the patients on their pathology in function of the movement quantification measured with MoCap and Electromyography. The aim of this research is to measure in a combined way the action potentials by sEMG and the amplitudes of displacement of the markers in motion capture, for movements determined in a population of patients presenting a facial pathology, in order to compare them with reference values obtained in healthy subjects. In a second step, the aim will be to study if there is a link between the way the patient looks at his pathology and the results of his management (treatment, rehabilitation) which will be quantitatively evaluated thanks to MoCap and sEMG.

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Key information

Conditions

Electromyography Eye-tracking Facial Palsy Facial Paralysis Mouth Diseases Nervous System Diseases Neurologic Manifestations Paralysis Pathological Conditions, Signs and Symptoms Signs and Symptoms Stomatognathic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

CHU Amiens Picardie

Amiens, Picardie, 80054, France

Location status: Recruiting

Location contact

Emilien Colin, Dr

SUB_INVESTIGATOR

François-Régis Sarhan, DR

SUB_INVESTIGATOR

Félix Marcellin, Dr

SUB_INVESTIGATOR

Stéphanie DAKPE, Dr

CONTACT

[email protected]

+33322668322

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Subjects with no known facial pathology (healthy volunteers) OR
  • Patients with peripheral facial palsy, irrespective of grade, whether or not previously treated
  • Subject with written informed consent
  • Subject over 18 years of age
  • Subject affiliated to a social security scheme

Exclusion criteria

  • Subjects with severe skin disorders that do not allow the application of electrodes or photo reflective markers
  • Subjects with speech disorders making it impossible to pronounce the sounds [o] and [pu]
  • Subject unable to provide written informed consent
  • Subjects under guardianship, curators or safeguard of justice

Treatment and study plan

dental impressions

Other

dental impressions

Simultaneous MoCap and EMG acquisition

Other

Simultaneous MoCap and EMG acquisition

Eye-tracking acquisition for pathological subjects

Other

Eye-tracking acquisition for pathological subjects

Follow-up visit for pathological subjects

Other

Follow-up visit for pathological subjects

Primary outcomes

  1. determination of baseline values of facial mimicry (in millimetres) in healthy volunteers

    Time frame: one month

    determination of baseline values of facial mimicry (in millimetres) in healthy volunteers

  2. determination of baseline values of eye-tracking (in millimetres) in healthy volunteers

    Time frame: one month

    determination of baseline values of eye-tracking (in millimetres) in healthy volunteers

  3. determination of the maximum range of motion of facial mimicry (in millimetres) in patients

    Time frame: one year

    determination of the maximum range of motion facial mimicry (in millimetres) in patients

  4. determination of the maximum range of motion of eye-tracking (in millimetres) in patients

    Time frame: one year

    determination of the maximum range of motion of eye-tracking (in millimetres) in patients

Study contacts

Contact information is provided by the study sponsor or research team.

Stéphanie Dakpé, Pr

CONTACT

[email protected]

03 22 08 90 50

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire, Amiens

Other

Registry information

Official study title

Multimodal Quantified Analysis of Facial Movements: Comparison Between Pathological

Acronym: AQ2MF

Important dates

Study start
2022
Primary completion
2027
Study completion
2028
First posted
Oct 14, 2022
Registry last updated
May 28, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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