Motor Evoked Potential in the Affected Upper Limb Predicts the Potential of Motor Recovery in Subacute Stroke Patients

Stroke is the third common cause of adult disability in dveloped countries. Early identification of the potential for motor recovery is important to avoid 'learned disuse' and to initiate appropriate therapy with achievable goals. The current cohort study focuses on those patients with SAFE <8 and using motor evoked potentials (MEPs) to improve on prognostication of upper limb motor recovery among subacute stroke patients in a local stroke population.

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Key information

Conditions

Stroke, Subacute Brain Diseases Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Nervous System Diseases Stroke Vascular Diseases

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Rehabilitation, Kowloon Hospital

Hong Kong

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

First stroke with hemiparesis or hemiplegia with SAFE <8

Exclusion criteria

contra-indication to TMS or MRI, history of seizure, pregnancy and mentally unfit to understand the consent

Treatment and study plan

MEPs induced by TMS

Diagnostic Test

Using TMS induced MEPs over motor cortex of the affected side to predict motor recovery potentials

Primary outcomes

Action Research Arm Test

Time frame: Change of Baseline Action Research Arm Test at 12 weeks post-stroke

Upper limb functional test

Sponsors and collaborators

Lead sponsor

Hospital Authority, Hong Kong

Other Gov

Registry information

Important dates

Study start: 2017
Primary completion: 2021
Study completion: 2021
First posted: Aug 9, 2017
Registry last updated: May 26, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed