Modified vs. Conventional Laparoscopic TAPP for Inguinal Hernia

This study aims to compare the outcomes of two laparoscopic techniques for repairing inguinal hernias: the modified tumescent technique (MT-TAPP) and the conventional laparoscopic transabdominal preperitoneal technique (CL-TAPP). The primary goal is to determine which technique provides better outcomes in terms of operative time, ease of pre-peritoneal space dissection, postoperative pain, and the formation of seromas. The study will involve 60 patients diagnosed with unilateral inguinal hernias, randomly assigned to either group. Participants in Group A will undergo the MT-TAPP procedure, which involves pre-peritoneal infiltration of a local anesthetic solution to improve dissection and reduce pain. Group B will undergo the standard CL-TAPP procedure. Data will be collected on various outcome measures and analyzed to identify which technique leads to quicker recovery, less postoperative pain, and fewer complications. The results of this study will help guide surgical decisions and improve patient outcomes in inguinal hernia repair.

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Key information

Conditions

Inguinal Hernia Repair

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age: 18 to 50 years.
Gender: Both male and female participants.
Condition: Diagnosed with unilateral inguinal hernia (as per operational definition).
Health Status: ASA I-III (American Society of Anesthesiologists physical status classification), indicating that the patient is fit for surgery.
Consent: Participants must be able to provide informed consent to participate in the study.

Exclusion criteria

Femoral Hernias.
Incarcerated or Strangulated Hernia.
Recurrent Hernias (as per medical record).
Serious Systemic Diseases:
Conditions such as heart failure or coagulation problems (e.g., PT > 15 sec).
ASA III-V classification, indicating a higher risk for surgery.
Pregnancy (if applicable).
Allergy to Anesthesia or the substances used in the tumescent solution (lidocaine, epinephrine, saline).
Uncontrolled Diabetes or other medical conditions that might interfere with the healing process.

Treatment and study plan

Modified Tumescent Laparoscopic TAPP (MT-TAPP) for the first group.

Other

In this intervention, participants will undergo laparoscopic inguinal hernia repair using the modified tumescent technique. This technique involves pre-peritoneal infiltration of a solution containing lidocaine, epinephrine, and saline. The tumescent solution is injected into the peritoneum to create a "tumescent" effect, making the tissues easier to dissect and reducing bleeding. This approach aims to improve surgical visibility, reduce operative time, minimize postoperative pain, and shorten the learning curve for less experienced surgeons. The rest of the procedure follows the standard laparoscopic TAPP repair, with mesh placement and peritoneal closure.

Conventional Laparoscopic TAPP (CL-TAPP)

Other

In this intervention, participants will undergo the conventional laparoscopic transabdominal preperitoneal (TAPP) hernia repair. This standard technique involves placing three ports to access the inguinal region, followed by dissection of the pre-peritoneal space and placement of a mesh to repair the hernia. The conventional method does not use tumescent infiltration and relies solely on the surgeon's skill to navigate the anatomical structures. This approach is well-established and commonly used in inguinal hernia repairs, but it may be associated with longer operative times and more postoperative pain compared to the modified technique.

Primary outcomes

Pain Score

Time frame: Recorded 24 hours post-surgery.

A score of 0 represents no pain, while a score of 10 represents the worst pain.
Seroma Formation:

Time frame: Presence or absence of seroma, assessed during the 7-day postoperative follow-up.

Study contacts

Contact information is provided by the study sponsor or research team.

Dr. Taseen Imran

CONTACT

[email protected]

923045079008

Sponsors and collaborators

Lead sponsor

University of Health Sciences Lahore

Other

Registry information

Official study title

A Randomized Controlled Trial Comparing Modified Tumescent vs. Conventional Laparoscopic TAPP for Inguinal Hernia Repair

Important dates

Study start: 2026
Primary completion: 2026
Study completion: 2026
First posted: Jan 28, 2026
Registry last updated: Jan 28, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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