Mobile-Based Telemedicine and Health-Related Quality of Life Among Patients With Chronic Heart Failure (MOBILE-HF)

Chronic heart failure (CHF) is a long-term cardiovascular condition that significantly impairs functional capacity and quality of life. Patients often experience persistent symptoms, reduced daily activity, and frequent hospital visits, particularly in settings with limited access to continuous follow-up care.

This study will evaluate the effectiveness of a mobile-based telemedicine intervention on health-related quality of life among CHF patients attending follow-up care at Menelik II Comprehensive Specialized Hospital, Addis Ababa, Ethiopia.

A quasi-experimental design with a nonequivalent control group pre-test and post-test approach will be used. A total of 70 eligible adult CHF patients will be included and assigned to either an intervention group (n = 35) or a comparison group (n = 35).

The intervention group will receive an 8-week mobile-based telemedicine program in addition to routine care. The program includes scheduled phone calls, text messages, and WhatsApp-based communication providing education, self-care guidance, medication adherence support, lifestyle modification advice, and symptom monitoring. The comparison group will receive routine standard care only.

Health-related quality of life will be measured at baseline and after 8 weeks using the Minnesota Living with Heart Failure Questionnaire (MLHFQ). The main outcome is the change in HRQoL between the two groups after the intervention period.

Data will be analyzed to determine the effect of the intervention on quality of life outcomes.

This study is expected to provide evidence on whether mobile-based telemedicine can improve patient-reported outcomes in CHF management and support its integration into routine cardiac care in resource-limited settings.

Inclusion criteria

• Adults aged 18-65 years who will be diagnosed with CHF (NYHA class II⁃III)
• Patients with reduced left ventricular ejection fraction LVEF ≤ 40%
• Patient who will have access to a mobile phone and will be able to use it
• Patients who will be able to communicate in Amharic, Oromic, or English
• Patients who will provide written informed consent
• Patients who will be diagnosed with HF lasting ≥ 6 months, to be confirmed by echocardiography and clinical assessment
• Patients with no contraindications for mild to moderate physical activity

Exclusion criteria

• Patients with NYHA class IV or who will require intensive care at enrollment
• Patients with other severe medical conditions (e.g., end-stage renal disease, & end stage liver disease)
• Patients with severe cognitive impairment or psychiatric illness that will interfere with participation
• Patients already enrolled in another telemedicine or intervention study
• Pregnant and lactating women