Misoprostol
Drugcomparison of orally administered 600mcg of misoprostol to either sublingually administered 400mcg or Manual Vacuum Aspiration (MVA)
Other names: Cytotec
NCT Number: NCT00670761
This randomized study will examine the efficacy, safety and acceptability of misoprostol for treatment of incomplete abortion.
Women diagnosed with incomplete abortion will be randomized to receive one of the following regimens:
In Tanzania and Mozambique:
1. 600 mcg of oral misoprostol in one dose, or 2. Standard surgical treatment (MVA)
In Moldova and Madagascar:
1. 600 mcg of oral misoprostol in one dose, or 2. 400 mcg of sublingual misoprostol in one dose.
In Burkina Faso and Vietnam:
1. 400 mcg of sublingual misoprostol in one dose.
We hypothesize that treatment of incomplete abortion with either 400 mcg sublingual misoprostol, 600 mcg oral misoprostol or MVA are equally effective in evacuating the uterus.
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Notify Me18 year and older
Female
Interventional
Not applicable
Hôpital de District Sanitaire Dandé, Bobo-Dioulasso, Burkina Faso
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
All women would have been advised to have surgical evacuation of the uterus if misoprostol was not available.
Exclusion criteria
comparison of orally administered 600mcg of misoprostol to either sublingually administered 400mcg or Manual Vacuum Aspiration (MVA)
Other names: Cytotec
comparison of orally administered 600mcg of misoprostol to either sublingually administered 400mcg or Manual Vacuum Aspiration (MVA)
Time frame: one week after initial treatment with the option of an additional week
Gynuity Health Projects
Other
Misoprostol for the Treatment of Incomplete Abortion: Comparison of Treatment Options
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