The University of Queensland
Brisbane, Queensland, 4072, Australia
NCT Number: NCT04786405
This trial aims to determine the effects and mechanisms (mediators and moderators) of brief training in mindfulness meditation versus clinical hypnosis on acute, experimental pain.
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Notify Me18 year and older
All sexes
Interventional
Phase 2
Brisbane, Queensland, 4072, Australia
Participants (N=200 with complete data) will be healthy undergraduate students or community-based individuals. An experimental, randomised trial will be implemented, with participants randomly assigned to either five daily, 20-minute mindfulness meditation sessions or clinical hypnosis sessions. Repeated measures and experimental pain manipulation will be implemented. Aim 1 is to examine the effects of these two treatments on experimental pain outcomes. Aim 2 is to examine the moderators of these effects. Aim 3 is to determine the mediators underlying improved experimental pain outcomes. Results will refine theory and will inform the future streamlining of treatments to target those mechanisms shown to be of most critical importance.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
These exclusion criteria are standard when using a cold pressor task in a healthy undergraduate population and ensure safe procedures to mitigate any potential risks.
Participants in the mindfulness meditation condition will practice a breath and body focused meditation.
Participants in clinical hypnosis will be guided in a hypnosis practice with suggestions tailored towards shifting pain appraisals.
Time frame: Change from Experimental Session 1 (Day 1) to Experimental Session 5 (Day 5)
Numerical rating scale in response to exposure to a cold pressor task.
Time frame: Change from Experimental Session 1 (Day 1) to Experimental Session 5 (Day 5)
Numerical rating scale in response to exposure to a cold pressor task.
Time frame: Change from Experimental Session 1 (Day 1) to Experimental Session 5 (Day 5)
How long (in seconds) participants tolerate the cold pressor task with the time starting at the point of immersion and stopping when the hand, wrist and forearm were withdrawn from the refrigerated water.
Time frame: Change from Experimental Session 1 (Day 1) to Experimental Session 5 (Day 5)
Heart rate data
Time frame: Change from Experimental Session 1 (Day 1) to Experimental Session 5 (Day 5)
A computer based task that has been developed to allow assessment of the functioning of the three major attentional networks; alerting, orienting, and executive attention.
Time frame: Change from Experimental Session 1 (Day 1) to Experimental Session 5 (Day 5)
A computer based task that has been developed to allow assessment of three types of mind wandering.
Time frame: Change from Experimental Session 1 (Day 1) to Experimental Session 5 (Day 5)
Five Facet Mindfulness Questionnaire-Short Form
Time frame: Change from Experimental Session 1 (Day 1) to Experimental Session 5 (Day 5)
Pain Catastrophizing Scale
Time frame: Change from Experimental Session 1 (Day 1) to Experimental Session 5 (Day 5)
Pain Appraisal Inventory
Time frame: Change from Experimental Session 1 (Day 1) to Experimental Session 5 (Day 5)
Pain-Related Cognitive Process Questionnaire34
Time frame: Baseline score at Experimental Session 1 (Day 1)
Stanford Clinical Hypnotizability Scale
Time frame: Baseline score at Experimental Session 1 (Day 1)
Treatment Expectations Questionnaire
The University of Queensland
Other
An Experimental, Randomized Trial Comparing Mindfulness Meditation Versus Clinical Hypnosis for Acute Pain: a Test of Effects and Mechanisms
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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