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Completed

NCT Number: NCT07297056

Mindfulness Psychoeducation for Bipolar Disorder

This randomized controlled experimental study investigates the effectiveness of a mindfulness-based psychoeducation program on mindfulness, self-compassion, and forgiveness among individuals diagnosed with bipolar disorder. Bipolar disorder is a chronic psychiatric condition characterized by fluctuations in mood, energy, and functional capacity, often accompanied by emotional dysregulation, impaired insight, and challenges in interpersonal relationships. Psychosocial interventions that cultivate emotional awareness and adaptive coping may support recovery and enhance long-term functioning.

In this study, 40 clinically stable patients with bipolar disorder were randomly assigned to either an experimental group (n=20) or a control group (n=20). The experimental group received a structured mindfulness-based psychoeducation program, while the control group received no additional intervention beyond usual care. Participants completed pre- and post-intervention assessments using a personal information form, the Mindfulness Scale, the Self-Compassion Scale-Short Form, and the Heartland Forgiveness Scale.

Findings demonstrated that individuals who participated in the mindfulness-based psychoeducation program showed significantly greater improvements in mindfulness, self-compassion, and forgiveness compared with the control group. These results suggest that integrating mindfulness-based psychoeducation into routine care may promote emotional resilience, enhance illness insight, support symptom management, and strengthen interpersonal functioning in individuals with bipolar disorder.

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Söke Fehime Faik Kocagöz Hospital

Aydin, Söke, 09200, Turkey (Türkiye)

About this study

Bipolar disorder is a chronic and recurrent psychiatric condition characterized by significant fluctuations in mood, energy levels, and functional capacity. Although pharmacological treatment remains the cornerstone of managing manic and depressive episodes, many individuals continue to experience residual symptoms, emotional dysregulation, heightened stress reactivity, and interpersonal difficulties even during periods of clinical stability. These challenges highlight the need for holistic approaches that address not only symptom reduction but also emotional regulation, self-awareness, and psychological well-being.

Mindfulness-based interventions have gained increasing attention as a complementary therapeutic approach for individuals living with bipolar disorder. Mindfulness practices cultivate the ability to observe internal experiences-thoughts, emotions, and bodily sensations-with openness, acceptance, and non-judgment. This enhanced awareness may reduce automatic emotional reactions, support early recognition of mood changes, and promote more adaptive coping strategies. By helping individuals respond rather than react to internal and external stressors, mindfulness may foster a sense of emotional balance and psychological resilience that is particularly valuable in bipolar disorder.

A key component closely linked to mindfulness is self-compassion, which involves treating oneself with kindness, understanding, and emotional warmth during times of difficulty or perceived inadequacy. Individuals with bipolar disorder often struggle with self-criticism, guilt, and negative self-appraisal stemming from the chronic and disruptive nature of the illness. Enhancing self-compassion may therefore help reduce emotional distress, facilitate more adaptive self-management, and strengthen long-term recovery-oriented functioning.

Forgiveness-toward oneself, others, and uncontrollable life circumstances-represents another important mechanism that may contribute to emotional healing in bipolar disorder. Difficulties associated with the illness may lead to strained relationships, unresolved emotional conflicts, or lingering feelings of resentment or self-blame. Developing forgiveness may promote emotional release, reduce psychological burden, and support healthier interpersonal dynamics.

The mindfulness-based psychoeducation program evaluated in this study integrates these components into a structured framework designed to enhance both emotional skills and illness-related insight. The program includes guided mindfulness practices such as breathing awareness and body scan exercises, psychoeducation modules that address symptom patterns and mood regulation, and reflective activities aimed at cultivating compassionate awareness and forgiveness. Through these combined elements, the intervention seeks to strengthen self-regulation capacities, promote acceptance-based coping, and improve psychosocial well-being in individuals with bipolar disorder.

By targeting mindfulness, self-compassion, and forgiveness simultaneously, the program offers a comprehensive approach to supporting emotional stability and personal recovery. This integrated model has the potential to enhance illness management, improve interpersonal functioning, and reduce the psychological burdens commonly experienced by individuals living with bipolar disorder.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosis of bipolar disorder according to DSM-5 criteria
  • Age between 18 and 65 years
  • Clinically stable for at least the past 3 months
  • Able to communicate, read, and understand Turkish
  • Receiving outpatient psychiatric follow-up
  • Willingness to participate and provide informed consent

Exclusion criteria

  • Presence of acute psychotic symptoms requiring immediate hospitalization
  • Comorbid intellectual disability, neurological disorder, or severe cognitive impairment
  • Substance or alcohol dependence within the last 6 months
  • Participation in any mindfulness-based or psychoeducational program within the last year
  • Severe visual or hearing impairment preventing participation
  • Any condition judged by the clinician to contraindicate participation in group sessions

Treatment and study plan

Mindfulness-Based Psychoeducation Program

Other

A structured 8-session mindfulness-based psychoeducation program including mindfulness exercises, psychoeducation, breathing techniques and adherence-support strategies.

Routine care

Other

Standard outpatient psychiatric care delivered by the clinic. No additional psychoeducation or mindfulness intervention is provided.

Primary outcomes

  1. Change in Mindfulness Level (Mindful Attention Awareness Scale)

    Time frame: Baseline and 8 weeks

    Mindfulness level was assessed using the Mindful Attention Awareness Scale (MAAS), a self-report questionnaire consisting of 15 items. Total scores range from 15 to 90, with higher scores indicating greater levels of mindfulness. The outcome measure represents the change in total MAAS score from baseline to post-intervention.

Secondary outcomes

  1. Between-group Differences in Post-intervention Mindfulness and Treatment Adherence Scores

    Time frame: 8 weeks

    Between-group differences in post-intervention scores were evaluated using the Mindful Attention Awareness Scale (MAAS) and the Medication Adherence Rating Scale (MARS).

    Mindfulness was assessed with the MAAS, a 15-item self-report scale with total scores ranging from 15 to 90, where higher scores indicate greater mindfulness.

    Treatment adherence was assessed using the MARS, which consists of 10 items, with total scores ranging from 0 to 10, where higher scores indicate better medication adherence.

    The outcome measure represents the comparison of post-test total scores between the experimental and control groups at the end of the intervention.

  2. Post-intervention Mindfulness and Treatment Adherence Scores Between Groups

    Time frame: 8 weeks

    Post-intervention differences between the experimental and control groups were evaluated using the following scales:

    Mindfulness: Assessed with the Mindful Attention Awareness Scale (MAAS), a 15-item self-report scale with total scores ranging from 15 to 90. Higher scores indicate greater mindfulness.

    Treatment Adherence: Assessed with the Medication Adherence Rating Scale (MARS), a 10-item self-report scale with total scores ranging from 0 to 10. Higher scores indicate better adherence to prescribed treatment.

    The outcome measure represents the comparison of post-test total scores between groups at the end of the 8-week intervention.

Sponsors and collaborators

Lead sponsor

Ömer USLU

Other

Registry information

Official study title

The Effect of Mindfulness-Based Psychoeducation Programme on Mindfulness, Self-Compassion and Forgiveness Tendencies of Patients With Bipolar Disorder: A Randomised Controlled Trial

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Dec 22, 2025
Registry last updated
Dec 31, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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