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OpenTrials
Completed

NCT Number: NCT00165282

Mindfulness Meditation in Bone Marrow Transplantation

The main purpose of this study is to examine techniques to help patients cope better with the stem cell/bone marrow transplant procedure.

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Key information

Age range

21 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2 / Phase 3

Primary location

Emory University, Atlanta, Georgia, United States

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About this study

Patients will be assigned to one of three study groups:

  • receives the normal standard care;
  • meets with an oncology nurse educator, in addition to the regular nurses on the transplant team. The nurse educator will provide information and answers to patient's questions about the stem cell/bone marrow transplant experience; or
  • is taught mindfulness meditation by a nurse who is trained to be a mindfulness instructor and by an audio CD.

Mindfulness meditation is a technique that may help in coping with the stress and difficulties associated with cancer and undergoing a stem cell/bone marrow transplant. It involves learning to be in the present moment by paying attention to your breathing, sights, and sounds, and to sensations you may be experiencing, or thoughts and feelings you may be having.

Mindfulness meditation has been shown to be helpful to patients in the clinic who have cancer and other medical conditions.

Patients, regardless of random group assignment, will complete a questionnaire 8 different times, from before they are admitted to the hospital until 6 months after discharge.

Patients will also provide two urine samples while in the hospital to measure the levels of stress hormones present in the urine.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Autologous stem cell transplantation for hematologic malignancy
  • First transplant
  • 21 years of age or older
  • Speaks and understands English

Exclusion criteria

  • Planned tandem (more than one) transplant
  • Taking corticosteroids on a regular basis for a chronic condition
  • Prior formal mindfulness meditation training
  • Significant cognitive impairment and/or confirmed psychosis or thought disorder

Treatment and study plan

Mindfulness Training

Behavioral

Taught mindfulness meditation by mindfulness instructor (trained health care professional/RN) and audio c/d

Nurse education

Behavioral

Meets with oncology nurse to have questions answered about medical treatments and side effects

Primary outcomes

  1. Psychological functioning

    Time frame: 1 year

Secondary outcomes

  1. Number of days to bone marrow engraftment

    Time frame: 1 year

  2. Medication use

    Time frame: 1 year

  3. Urinary stress hormones (cortisol and catecholamines)

    Time frame: 1 year

  4. Transplant related complications

    Time frame: 1 year

  5. Hospital length of stay and re-hospitalizations

    Time frame: 1 year

  6. Physical symptoms

    Time frame: 1 year

  7. Quality of life

    Time frame: 1 year

Sponsors and collaborators

Lead sponsor

Emory University

Other

Collaborators

  • Dana-Farber Cancer Institute
  • University of Massachusetts, Worcester

Registry information

Important dates

Study start
2005
Primary completion
2010
Study completion
2011
First posted
Sep 14, 2005
Registry last updated
Nov 28, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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