Microvascular Reactivity.

This study attempts to test capillary responses to various challenges without the need for iontophoresis (electrical current).

Completed

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Key information

Conditions

Diabetes Aneurysm Cardiovascular Diseases Diabetes Mellitus Endocrine System Diseases Eye Diseases Glucose Metabolism Disorders Metabolic Diseases Nutritional and Metabolic Diseases Retinal Diseases Retinopathy Vascular Diseases Vascular Pathology

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Yale School of Medicine

New Haven, Connecticut, 06510, United States

About this study

Studies of microvascular responsiveness often employ iontophoresis to fascilitate drug absorption. Iontophoresis is a confounding stimulus in such studies, and we are attempting to create tests of the microvasculature that do not require iontophoretic drug delivery.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

diabetic. -

Exclusion criteria

not on nitrates or mydriatic eye drops within 48 hours.

Treatment and study plan

Laser Doppler Flowmetry with topical acetylcholine and nitroglycerin

Device

Sponsors and collaborators

Lead sponsor

Yale University

Other

Registry information

Official study title

Transdermal Application of Acetylcholine and Nitroglycerin Without Iontophoresis.

Important dates

Study start: 2005
Study completion: 2005
First posted: Nov 29, 2005
Registry last updated: Oct 6, 2006

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed