Skip to main content
OpenTrials
Completed

NCT Number: NCT00590330

Microbial Community Composition and Dynamics in Lungs of Cystic Fibrosis Sibling Pairs

The purpose of this study is to identify all the bacterial species present in the respiratory tracts of patients with Cystic Fibrosis (CF), and to connect them with clinical information. Traditional culture methods of throat swab and sputum samples can only identify the most prevalent bacteria in samples, those of which there are over about 5 million bacteria per teaspoon. A recently developed method has been found to be more sensitive and can detect up to several hundred bacterial species in throat swab or sputum sample of individual CF patients.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities Digestive System Diseases Genetic Diseases, Inborn Infant, Newborn, Diseases Lung Diseases Pancreatic Diseases Respiratory Tract Diseases

Age range

1 year–16 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Children's Hospital

Boston, Massachusetts, 02115, United States

About this study

This study does not include testing of any investigational drugs and this is a noninvasive study requiring only a sputum/swab sample paired with information contained in the routine clinic letters and laboratory results your CF physicians obtain at your regular clinic visits.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Between the ages of 1-16 upon enrollment
  • Diagnosis of Cystic Fibrosis

Exclusion criteria

  • None

Treatment and study plan

Primary outcomes

  1. To identify all the bacterial species present in the respiratory tracts of patients with Cystic Fibrosis (CF).

    Time frame: 2 years

Sponsors and collaborators

Lead sponsor

Boston Children's Hospital

Other

Collaborators

  • Harvard University

Registry information

Important dates

Study start
2007
Primary completion
2009
Study completion
2009
First posted
Jan 10, 2008
Registry last updated
May 13, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.