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Completed

NCT Number: NCT01206153

Metformin for Treatment Antipsychotic Induced Amenorrhea in Female Schizophrenic Patients

Antipsychotics such as risperidone could induce amenorrhea in schizophrenic patients. The investigators conducted a randomized, placebo-controlled study to test the efficacy of metformin for antipsychotic induced amenorrhea in schizophrenia patients.

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Key information

Conditions

Amenorrhea Menstruation Disturbances Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year–40 year

Sex eligibility

Female

Study type

Interventional

Phase

Phase 4

Primary location

Institute of Mental Health of The Second Xiangya Hospital, Central South University

Changsha, Hunan, 410011, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • schizophrenia patient
  • amenorrhea for more than three months after antipsychotic treatment

Exclusion criteria

  • liver or renal diseases
  • pregnant or lactating women
  • cardiovascular diseases
  • hypertension or diabetes mellitus

Treatment and study plan

metformin

Drug

Primary outcomes

  1. prolactin level

    the outcome measure assess a efficacy.

Secondary outcomes

  1. fasting glucose

Sponsors and collaborators

Lead sponsor

Central South University

Other

Registry information

Official study title

Metformin for Treatment Antipsychotic Induced Amenorrhea in Female Schizophrenic Patients: a Double Blind, Placebo-controlled Study

Important dates

Study start
2008
Primary completion
2010
Study completion
2010
First posted
Sep 21, 2010
Registry last updated
Sep 21, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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