Skip to main content
OpenTrials
Recruiting

NCT Number: NCT07167667

Median Nerve Thickness of the Carpal Tunnel Syndrome After Two Different Physiotherapy Modalities

The study plans to include a total of 60 patients diagnosed with carpal tunnel syndrome. Patients will be divided into two groups according to the treatment they receive. One group will receive only paraffin treatment, while the other group will receive only ESWT treatment. ESWT will be applied for a total of 5 sessions. Paraffin will be applied for a total of 10 sessions. As assessment tools;

* Measurement of median nerve thickness with ultrasound * Electromyography * Visual Analog Scale * Short Form-36

Evaluations will be made twice by a specialist physician before and after the treatments.

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Carpal Tunnel Syndrome (CTS) Carpal Tunnel Syndrome Cumulative Trauma Disorders Median Neuropathy Mononeuropathies Nerve Compression Syndromes Nervous System Diseases Neuromuscular Diseases Peripheral Nervous System Diseases Sprains and Strains Wounds and Injuries

Age range

30 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Baltalimani Metin Sabanci Bone Diseases Training and Research Hospita

Istanbul, Turkey (Türkiye)

Location status: Recruiting

Location contact

Esra Sonbahar Bolat, Physican

CONTACT

[email protected]

+905052686709

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Individuals between the ages of 30-60 who have been diagnosed with CTS by a specialist physician according to international criteria (Those between Stages 1-3),
  • Those who have complaints of numbness, tingling, and pain in the first three fingers and half of the fourth finger,
  • Phalen Test and Tinel sign or Durkan Test being positive
  • Patients who will receive 5 sessions of ESWT application prescribed by a Physical Medicine and Rehabilitation Specialist Physician (for the ESWT group)
  • Patients who have been recommended 10 sessions of Paraffin application by a Physical Medicine and Rehabilitation Specialist Physician (for the Paraffin group)

Exclusion criteria

  • Presence of atrophy in the thenar muscles,
  • Insufficient sensory and motor response in the median nerve,
  • History of hand and/or wrist injury or surgery,
  • Those with cervical stenosis, cervical spondylosis, or cervical radiculopathy,
  • Corticosteroids in the carpal tunnel area within the last six months those who have had an injection,
  • Pregnancy or diabetes, renal failure, rheumatoid arthritis or hypothyroidism

Treatment and study plan

paraffin bath

Other

Patients' hands will be dipped into the paraffin bath 8-10 times.

Extracorporeal Shock Wave Therapy

Other

The patients will be treated with a sound wave pulse frequency of 15 Hz, an intensity of 1.5 bar, and a total number of pulses of 2000 for one session.

Primary outcomes

  1. Median Nerve Thickness

    Time frame: Baseline

    Median nerve thickness will be measured by ultrasound

  2. Median Nerve Thickness

    Time frame: 5 days later for the first ESWT intervention and 10 days later for the first Paraffin Intervention

    Median nerve thickness will be measured by ultrasound

Secondary outcomes

  1. Electromyography

    Time frame: Baseline

    EMG will be used to diagnose carpal tunnel.

  2. Visual Analog Scale

    Time frame: Baseline

    It will be used to assess pain intensity.

  3. Visual Analog Scale

    Time frame: 5 days later for the first ESWT intervention and 10 days later for the first Paraffin Intervention

    It will be used to assess pain intensity.

  4. Short Form-36

    Time frame: Baseline

    It will be used to evaluate patients' quality of life.

  5. Short Form-36

    Time frame: 5 days later for the first ESWT intervention and 10 days later for the first Paraffin Intervention

    It will be used to evaluate patients' quality of life.

Study contacts

Contact information is provided by the study sponsor or research team.

Esra Sonbahar Bolat, Physician

CONTACT

[email protected]

+9005052686709

Sponsors and collaborators

Lead sponsor

Emre Şenocak

Other

Registry information

Official study title

Investigation of the Effects of Two Different Physiotherapy Modalities on Median Nerve Thickness, Electrophysiological Activity, Pain Intensity and Quality of Life in Patients With Carpal Tunnel Syndrome - An Observational Study

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Sep 11, 2025
Registry last updated
Sep 11, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.