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OpenTrials
Completed

NCT Number: NCT00416000

Mechanism and Prevention of Remote Organ Injury Following Ruptured Aortic Aneurysm

It has been estimated that 80% of deaths from abdominal aortic aneurysms results from rupture. Endovascular Aneurysm Repair (EVAR) has been applied to RAAA (Ruptured Abdominal Aortic Aneurysm) patients with reports of improvements. Despite the use of EVAR, patients have developed complications with lung and kidney function. This study will investigate certain biochemical processes that will potentially reduce these complications. Knowledge gained from this study may also be used to further research in this field through larger studies.

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Key information

Conditions

Abdominal Aortic Aneurysm Aneurysm Aortic Aneurysm Aortic Aneurysm, Abdominal Aortic Diseases Cardiovascular Diseases Vascular Diseases

Age range

30 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Toronto General Hospital

Toronto, Ontario, M5G 2C4, Canada

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Open/Elective EVAR patients

Exclusion criteria

  • Patients who do not present with abdominal aortic aneurysms or ruptured abdominal aortic aneurysm

Treatment and study plan

Primary outcomes

  1. Mortality

    Time frame: 30 days

Secondary outcomes

  1. multiple organ failure

    Time frame: 30 days

Sponsors and collaborators

Lead sponsor

University Health Network, Toronto

Other

Collaborators

  • The Physicians' Services Incorporated Foundation

Registry information

Official study title

Phase 1 Study of Complement Activation Following Ruptured Abdominal Aortic Aneurysm: Combining Human Observation With Animal Experimentation to Establish a Framework for Human Therapy

Important dates

Study start
2006
Primary completion
2010
Study completion
2010
First posted
Dec 27, 2006
Registry last updated
May 21, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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