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NCT Number: NCT07549815

Measuring the Changes of the Intraocular Pressure After Corneal Laser Refractive Surgery Using Different Techniques

To evaluate the changes that occur in the intraocular pressure after corneal refractive surgery either PRK , LASIK and femtosecond laser by using Corvis CT results and applanation tonometer

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Key information

Age range

19 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

About this study

This study will be prospective study. 50 Patients who will undergo refractive surgery referred from the out-patient clinic of Tanta University hospital between December 2025 and December 2026 will be included in the study . The patient will be randomly selected to do either LASIK, PRK or femtosecond laser LASIK

Patients who will undergo refractive surgery either PRK, LASIK or femtosecond laser with age between 19 and 35 years old , Myopia range from (-2.00 to -6.00 Diopter) and to maintain stability of the data we will use only the right eye of each patient will be included on the study

Kertoconus, Corneal scarring, Previous corneal infections, Minimum corneal thickness at the thinnest location less than 400 µm, History of uveitis or ocular allergy and Pre-existing glaucoma will be excluded from the study.

Age, sex, uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest and cycloplegic refraction, Slit lamp biomicroscopy, fundus examination , Central corneal thickness (CCT) and average Keratometer (K) data will be collected

Intraocular pressure will be measured by by two methods : Corvis CT and applanation tonometer for each patient and will be recorded, all the data will be collected before the refractive surgery and one month after refractive surgery

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age between 19 and 35 years old
  • Myopia range from (-2.00 to -6.00 Diopter) .

Exclusion criteria

  • Kertoconus.
  • Corneal scarring.
  • Previous corneal infections.
  • Minimum corneal thickness at the thinnest location less than 400 µm.
  • History of uveitis or ocular allergy.
  • Pre-existing glaucoma.

Treatment and study plan

Corvis machine

Other

Measuring intraocular pressure by different methods and compare the results

Primary outcomes

  1. Measuring intraocular pressure

    Time frame: -The data collected will be before that laser surgery and one month after surgery

    Intraocular pressure will be measured by in mmHg and by two methods : Corvis CT and applanation tonometer for each patient and will be recorded

Study contacts

Contact information is provided by the study sponsor or research team.

Dina Tadros, Ass Professor of Ophthalmology

CONTACT

[email protected]

+201224093354

Sponsors and collaborators

Lead sponsor

Tanta University

Other

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2027
First posted
Apr 24, 2026
Registry last updated
Apr 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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