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NCT Number: NCT07599020

Measuring the Changes of the Intraocular Pressure After Corneal Cross Linking Using Corvis CT

To evaluate the changes that occur in the intraocular pressure before and after corneal cross linking using Corvis CT.

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Key information

Age range

19 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

This study will be prospective study. 50 Patients will be included who will undergo corneal cross linking from the out-patient clinic of Tanta University hospital between December 2025 and December 2026 will be included in the study .

Patient with age 19 till 35 years old will be included

Patient with Corneal scarring, Previous corneal infections, Minimum corneal thickness at the thinnest location less than 400 µm, History of uveitis or ocular allergy and Pre-existing glaucoma will be excluded from the study

All patient will undergo full ophthalmological examination. including best corrected visual acuity, degree of myopia , average kertometry and intraocular pressure will be measured before and after cross linkage with three different techniques including Shiotz tonometry, appalanation tonometry and CORVIS machine

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who will corneal cross linking for mild degree of keratoconus, age between 19 and 35 years old

Exclusion criteria

  • Corneal scarring.
  • Previous corneal infections.
  • Minimum corneal thickness at the thinnest location less than 400 µm.
  • History of uveitis or ocular allergy.
  • Pre-existing glaucoma.

Treatment and study plan

Corvis Machine

Device

Measuring the intraocular pressure

Primary outcomes

  1. Intraocular pressure will be measured by using Corvis CT before cross linking and one month after cross linking

    Time frame: Through the end of the study in approximately one year

    Recording the intraocular pressure

Study contacts

Contact information is provided by the study sponsor or research team.

Tamer Ibrahim, Ass professor of ophthalmology

CONTACT

[email protected]

+201001243049

Sponsors and collaborators

Lead sponsor

Tanta University

Other

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2027
First posted
May 20, 2026
Registry last updated
May 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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