Skip to main content
OpenTrials
Completed

NCT Number: NCT02631369

Measuring Cyclotorsion on Scanning Laser Ophthalmoscopy (SLO)-Fundus Photographs

Pre-Study: Evaluation of the inter- and intrarater reliability of the integrated algorithm by Heidelberg Spectralis for measuring cyclotorsion on SLO-fundus fotographs, and assessment of the influence of measuring with or without eye tracker.

Study: Comparison of cyclotorsion measurements in patients with forth nerve palsy and in healthy controls on SLO-fundus fotographs using the integrated algorithm by Heidelberg Spectralis

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Trochlear Nerve Diseases Cranial Nerve Diseases Nervous System Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University Hospital Zurich, Dept of Ophthalmology

Zurich, Canton of Zurich, 8091, Switzerland

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ≥ 18 years old
  • best corrected visual acuity ≥ 0.8

Exclusion criteria

  • strabismus except for forth nerve palsy
  • previous strabismus surgery
  • monocle
  • best corrected visual acuity ≤ 0.6
  • hyperopia or myopia > 6dpt

Treatment and study plan

Heidelberg Spectralis OCT device

Device

Primary outcomes

  1. pre-study: reliability of repeated measurements of excyclotorsion in degrees on SLO-fundus fotographs

    Time frame: 3 months

    pre-study: inter- and intrarater reliability of the device with or without eye tracker; excyclotorsion in degrees (based on the line crossing the fovea and the center of the optic nerve head) as provided by the integrated algorithm by Heidelberg Spectralis

  2. study: excyclotorsion in degrees on SLO-fundus fotographs

    Time frame: 12 months

    study: comparison of cyclotorsion measurements in healthy controls compared to patients with forth nerve palsy; excyclotorsion in degrees (based on the line crossing the fovea and the center of the optic nerve head) as provided by the integrated algorithm by Heidelberg Spectralis

Secondary outcomes

  1. study: excyclotorsion in degrees on tangent screen, double maddox and fundus photographs

    Time frame: 12 months

    validation of the cyclotorsion measurement with the Heidelberg Spectralis device against tangent screen [degrees], double maddox [degrees] and fundus photographs [degrees]

Sponsors and collaborators

Lead sponsor

University of Zurich

Other

Registry information

Official study title

Measuring Cyclotorsion on Scanning Laser Ophthalmoscopy (SLO)-Fundus Photographs Using the Integrated Algorithm by Heidelberg Spectralis

Acronym: CySLO

Important dates

Study start
2015
Primary completion
2017
Study completion
2017
First posted
Dec 16, 2015
Registry last updated
Jun 13, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.