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NCT Number: NCT05495737

Meaning-Centered Psychotherapy at Home

The purpose of this study is to train nurses from the VNS Health Visiting Nurse Service to deliver Meaning-Centered Psychotherapy for Palliative Care Patients (MCP-PC) to homebound people, and to evaluate how effective MCP-PC is for people with cancer.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York, United States

Loading trial locations.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Participant Inclusion Criteria:

Nurses (all phases):

  • Per self-report, providing direct care services at VNS Health
  • Per self-report, fluent in English**
  • Per self-report, is age 18 or older

Patients (all phases):

  • Per health record and/or self-report, is a patient in the VNS Health home health agency division (post-acute care)
  • Per health record and/or self-report, is age 18 or older
  • Per health record, has a cancer diagnosis and a rating of ≥ 2 on Symptom Control Scale
  • Per health record and/or self-report, fluent in English**
  • Has a score of ≥ 4 on Callahan cognitive screener
  • Has a score of ≥ 4 on Distress Thermometer (N/A for Training Case Participants)
  • Language verification: For both nurses and patients, prior to enrollment, all will be asked the following two questions by a Clinical Research Coordinator (CRC) to verify

English fluency necessary for participation in the study:

  • How well do you speak English? (must respond "very well" or "well" when given the choices of Very well, Well, Not well, Not at all, Don't know, or Refused)
  • What is your preferred language for healthcare? (must respond English)

Participant Exclusion Criteria:

Nurses (all phases):

  • Per self-report, planning to leave position at VNS Health in the next 6 months

Patients (all phases):

  • Per health record and/or self-report, has a diagnosis of Alzheimer's, dementia, or other organic brain disorder and in the judgment of the PIs is unable to meaningfully participate.
  • Per health record, has impaired decision-making capacity
  • Per health record and/or self-report, is permanently placed in a nursing home
  • Per health record and/or self-report, is currently receiving Hospice care

Treatment and study plan

Meaning-Centered Psychotherapy/MCP-PC Training

Behavioral

Two-Day MCP-PC Training for Nurses (including mock patient/simulation with actor) with a Pre- and Post-Training Assessment

Meaning-Centered Psychotherapy/MCP-PC

Behavioral

3 sessions, completed over the course of 3-6 weeks in the participant's home

Treatment As Usual/TAU

Behavioral

Research team will provide:

  • feedback about level of distress at time of screening
  • local referral for psychological care

Primary outcomes

  1. MPI Competency Ratings

    Time frame: 2 years

    Phase I portion: To refine the MCP-PC training and study procedures for homecare delivery by nurse interventionists as determined by providers' MPI Competency Ratings

Sponsors and collaborators

Lead sponsor

Memorial Sloan Kettering Cancer Center

Other

Registry information

Official study title

A Pragmatic Randomized Control Trial of Nurse-Delivered Brief Meaning Centered Psychotherapy for Homebound Palliative Care Patients

Important dates

Study start
2022
Primary completion
2026
Study completion
2026
First posted
Aug 10, 2022
Registry last updated
Sep 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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