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NCT Number: NCT07657546

MCG for Non-Obstructive Myocardial Ischemia

The aim of this prospective study is to identify Non-Obstructive Myocardial Ischemia of patients who have acute chest pain using Magnetocardiography.

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Qliu Hospital of Shandong University

Jinan, Shandong, 250012, China

Location status: Recruiting

Location contact

Chen

CONTACT

Jiaojiao Pang, Doctor

CONTACT

[email protected]

0086-0531-82165398

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18 years or older;
  • Patients with symptoms of myocardial ischemia such as angina pectoris, who have CAG showing <70% stenosis at the most severe site or CTA showing non-severe stenosis
  • Signed informed consent.

Exclusion criteria

  • Patients with absolute or relative contraindications to CFR-loaded myocardial perfusion, including acute myocardial infarction within 48 hours, significant left main coronary artery stenosis, bronchial asthma, and adenosine injection allergy;
  • Patients with Non-ischemic dilated cardiomyopathy, or hypertrophic cardiomyopathy, or moderate or severe valvular disease;
  • Patients with Hemodynamic instability (systolic blood pressure<90 mmHg, or who requires vasoactive drugs), or patients with tachyarrhythmia,

#degree atrioventricular block and above that have not returned to normal;

  • Patients who have severe renal abnormality with eGFR <30 ml/min, or patients who are on dialysis;
  • Patients with malignant tumors with predicted survival of less than 1 year;
  • Pregnant or breastfeeding women;
  • Patients who are unable to enter the MCG device, who are unable to perform MCG examination due to interference from metal implants or other reasons, or who are deemed by the investigators to be unsuitable for enrollment.

Treatment and study plan

Magnetocardiography

Device

Assessing the performance of magnetocardiography device for detecting non-obstructive myocardial ischemia using ultrasound coronary flow reserve (CFR) as the reference standard.

Primary outcomes

  1. Efficacy of MCG for the detection of Non-Obstructive Myocardial Ischemia

    Time frame: from the date of enrollment until the date of discharge, up to 30 days]

    Establishing an algorithm model of MCG in identifying Non-Obstructive Myocardial Ischemia, the efficacy of the model was assessed by sensitivity, specificity

Study contacts

Contact information is provided by the study sponsor or research team.

Jiaojiao Pang, Doctor

CONTACT

[email protected]

0086-0531-82165398

Sponsors and collaborators

Lead sponsor

Qilu Hospital of Shandong University

Other

Registry information

Official study title

Magnetocardiography in the Identification of Non-Obstructive Myocardial Ischemia of Patients With Acute Chest Pain

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jun 18, 2026
Registry last updated
Jun 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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