Management of Supraventricular Tachycardias in Children

Background

Supraventricular tachycardias (SVTs) are the most common arrhythmic events in children, with an estimated incidence of 13 per 100,000 per year before the age of 18. Few large patient cohorts have been reported, as most published studies are single-center. Large-scale studies come from medico-administrative databases, which lack the granularity needed for detailed analysis of outcomes according to the therapies used and the type of SVT.

Furthermore, although a large proportion of neonatal SVTs do not recur (spontaneous resolution of the accessory pathway), there are limited comparative data on the effectiveness of antiarrhythmic therapies specifically in children after the age of 1 year. Management therefore varies greatly, in part because current guidelines propose different therapeutic options based on low-level evidence.

Objectives:

* Describe the management of SVTs (antiarrhythmic therapies and catheter ablation) in children in France * Compare the effectiveness of different antiarrhythmic treatments according to age (<1 year and >1 year) and type of SVT * Analyze the incidence of adverse events and complications associated with antiarrhythmic treatments and catheter ablation

Completed

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Key information

Conditions

Supraventricular Arrhythmias Arrhythmias, Cardiac Cardiac Conduction System Disease Cardiovascular Diseases Children Heart Diseases Management Pathologic Processes Pathological Conditions, Signs and Symptoms Tachycardia Tachycardia, Supraventricular

Age range

0 year–18 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age <18 years at the time of the first documented supraventricular tachycardia episode

Exclusion criteria

Early postoperative supraventricular tachycardia (<30 days)
Age ≥18 years at the first documented supraventricular tachycardia episode
Fetal tachycardias without postnatal recurrence
Atrial extrasystoles without sustained runs (<30 seconds)

Treatment and study plan

Management of children with supraventricular tachycardias

Other

Observational analysis of the management of supraventricular tachycardias (antiarrhythmic drugs and catheter ablations)

Primary outcomes

Antiarrhythmic therapies

Time frame: At the time of the first supraventricular tachycardia recorded

Proportion of antiarrhythmic therapies used by age group (<1 year and >1 year)
Catheter ablation

Time frame: At the time of first episode of supraventricular tachycardia or after recurrence

Proportion of children referred for catheter ablation and age at ablation
Recurrence of supraventricular tachycardia

Time frame: At 1 year after antiarrhythmic drug initiation

Time between antiarrhythmic therapy initiation and first recurrence, according to treatment and age

Sponsors and collaborators

Lead sponsor

Paris Cardiovascular Research Center (Inserm U970)

Other Gov

Registry information

Official study title

Management of Supraventricular Tachycardias in Children: A National Multicenter Study

Important dates

Study start: 2000
Primary completion: 2025
Study completion: 2025
First posted: Dec 18, 2025
Registry last updated: Jan 2, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed