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OpenTrials
Completed

NCT Number: NCT03665324

Atrial Function and Supraventricular Arrhythmia of the Veteran Athlete.

Supraventricular arrhythmias (including atrial fibrillation) are the most common arrhythmias of the veteran athlete and have a major impact in terms of morbidity and mortality. Although moderate sports practice has been shown to decrease the occurrence of these arrhythmias, it has also been shown that very intense athletic activity is associated with an increased risk of developing atrial fibrillation. The pathophysiological mechanism is not clearly understood. However, it has already been shown that intensive sports practice leads to electrical and morphological atrial remodeling, which could be the cause of the occurrence of supraventricular arrhythmias for these athletes.

For sedentary patients, two major tools predict the risk of the onset of supraventricular arrhythmia: the electrocardiogram (ECG) and transthoracic echocardiography (ETT), particularly with the study of atrial function by the analysis of myocardial deformities.

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Key information

Conditions

Supraventricular Arrhythmias

Age range

35 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Rennes University Hospital

Rennes, 35000, France

About this study

No studies have tested these two tools for the evaluation of atrial remodeling of the veteran athlete to predict which ones are at risk of developing supraventricular arrhythmias.

However, the identification of predictive factors would make it possible to identify at-risk athletes and thus provide them with adapted sporting practice advice and personalized follow-up.

The aim of the study is to evaluate the relationship between atrial remodeling assessed by ECG and ETT with the occurrence of supraventricular arrhythmia by comparing an athlete group with supraventricular arrhythmia with a control group of healthy athletes.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Supraventricular arrhythmia group : Veteran athletes with documented paroxysmal supraventricular arrhythmias.
  • Control Group : Veteran athletes without documented supraventricular arrhythmia.

Exclusion criteria

  • Any cardiopathy (valvulopathy, coronary heart disease, etc.).
  • Minor patients,
  • Major patients subject to legal protection (legal safeguards, guardianship)
  • Persons deprived of their liberty
  • Patients opposed to the use of their personal data.

Treatment and study plan

Evaluation of the relationship between atrial remodeling evaluated by ECG and ETT with the occurrence of supraventricular arrhythmias

Other

Subjects will be retrospectively retrieved from the Sport Medicine Service of Rennes University Hospital database.

Medical data will then be collected from the athletes' medical records. The ECG present in the medical file will be reinterpreted to obtain the resting heart rate, the amplitude of the P wave, the morphology of the P wave and the duration of the PR space.

The data from the stress test will be found from reports in the medical records: resting heart rate, maximum heart rate, sustained peak load, arrhythmia during the test.

ETTs will be retrieved from the local server. They will be reinterpreted to collect anatomical and functional cardiac data necessary for the study.

Primary outcomes

  1. Study of atrial function by analysis of myocardial strain.

    Time frame: At the inclusion day

    Myocardial strain in extracted from ETT and compared between the two groups.

Sponsors and collaborators

Lead sponsor

Rennes University Hospital

Other

Registry information

Acronym: FA2V

Important dates

Study start
2017
Primary completion
2017
Study completion
2017
First posted
Sep 11, 2018
Registry last updated
Sep 11, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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