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Completed

NCT Number: NCT06983626

Management of Non Obstructive Azoospermia in Men

this study predicts the factors of successful micro testicular sperm extraction in azoospermia patients in male infertility

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Key information

Conditions

Male Infertility Azoospermia, Nonobstructive Genital Diseases Genital Diseases, Male Infertility Infertility, Male Male Urogenital Diseases Urogenital Diseases

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Medicine, South Valley University

Luxor, Qena Governorate, 83511, Egypt

About this study

primary outcomes: these factors were the age, testicular size, hormonal, evidence of varicocles and the out come of Micro_TESE secondary outcomes: make good decision for Micro-TESE with low economic laboratory and radiology requirement As every failed microTESE-ICSI procedure exposes the couple to an emotional, financial burden and increase the incidence of complication such as bleeding, hematoma and testicular atrophy

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Non obstructive Azoospermia with no genetic abnormalties as klinefelter syndrome

  • redo Micro TESE

Exclusion criteria

  • obstructive Azoospermia and bilateral congenital absent of vas

Treatment and study plan

micro-dissection testicular sperm extraction

Procedure

dissection of the seminefrous tubules under microscope to extract sperms

Other names: TESE, TESA, PESA

Primary outcomes

  1. Sperm Retrieval Success Rate and identification of Predictive Factors

    Time frame: 1st 1 year

    Determine which preoperative factors are significantly associated with successful sperm retrieval. These may include:

    Serum Follicle-Stimulating Hormone (FSH) Levels: Elevated FSH levels have been linked to reduced sperm retrieval success.

    And patient Age and testicular size to reach the best one to predict the success rate

Secondary outcomes

  1. Assess the success rates of ART procedures following sperm retrieval and complications

    Time frame: 2 years

    Assisted Reproductive Technology (ART) Outcomes

    Fertilization Rates: The percentage of oocytes successfully fertilized.

    Embryo Development: Quality and progression of embryos to the blastocyst stage.

    Clinical Pregnancy Rates: Confirmed pregnancies via ultrasound.

    Live Birth Rates: The ultimate success metric of ART procedures

    Complication Rates

    Monitor and document any complications arising from the sperm retrieval procedure, such as:

    Testicular Hematoma

    Infection

    Testicular Atrophy

Sponsors and collaborators

Lead sponsor

South Valley University

Other

Registry information

Official study title

Predictive Factors of Successful Micro-dissection Testicular Sperm Extraction For Patients With Non Obstructive Azoospermia

Acronym: azoospermia

Important dates

Study start
2022
Primary completion
2024
Study completion
2025
First posted
May 21, 2025
Registry last updated
May 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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