Management of Infant Digestive Disorders and Quality of Life

The objective of the study is to measure the evolution of the quality of life in infants between 0 and 5 months old, not breastfed and suffering from regurgitation or colic, following nutritional management of these disorders by a preparation for thickened infants, reduced in lactose content and supplemented with Lactobacillus reuteri DSM 17938. Quality of life is assessed using the QUALIN questionnaire

Inclusion criteria

Full-term infants (> 37 weeks gestation and <42 weeks gestation), less than 4 months of age at recruitment

• Infants with regurgitation and / or colic defined according to Rome IV criteria
• Non-breastfed infants
• Parents who understand and speak French fluently
• Parents agreeing to send their email address and having a computer tool (computer, tablet or smartphone) allowing them to complete the QoL questionnaires and the satisfaction questionnaire
• Parents having understood the protocol and the information given and having given the participation agreement including their acceptance to return for consultation with the same doctor after a period of 30 days.

Exclusion criteria

Infant born prematurely (<37 weeks)

• Intercurrent pathology other than a functional intestinal disorder which can by themselves cause, directly or as a result of treatments, a functional intestinal disorder: Study Management of infant digestive disorders and Quality of life

• Food allergy
• Digestive pathology (Gastroenteritis, celiac disease, high or low digestive malformations….)
• Heart failure, cyanogenic heart disease
• Chronic respiratory diseases (bronchopulmonary dysplasia, malformations, respiratory failure)
• Neurological pathologies (Cerebral palsy, intracranial hypertension, convulsive state)
• Congenital metabolic pathologies
• Genetic diseases
• Kidney malformations, Vesicoureteral reflux, Kidney failure.
• Drug treatment in progress and which will be continued during the study, other than vitamins (D, K, ...)
• Partial or total breastfeeding
• Infants already fed:
• with a hypoallergenic formula (HA)
• or with a high hydrolyzate of cow's milk proteins or formula based on rice protein hydrolyzate
• Growth retardation (weight and or height less than or equal to - 2 DS) or break in the weight curve (no weight gain or weight loss in the past month) Prescription of drugs or food supplements other than vitamins at the end of the visit