Evaluation Report of the Urea / Urine Creatinine as a Marker of Nutritional Status Predictive of ICU Care Associated Infections
NCT02911246
Brain Diseases, Brain Injuries
Nantes, France
View Trial DetailsNCT Number: NCT01132742
Malnutrition in children has even more severe consequences on disease course and long-term health than malnutrition in adults. According to prior studies, malnutrition affects about 15-30 % of hospitalized children in Europe (ESPGHAN 2005, Pawellek et al 2008, Joosten and Hulst 2008). However, available criteria for defining malnutrition in paediatric patients are inconsistent, not based on firm evidence, and not generally agreed upon. Current guidelines do not address assessment of and screening for childhood malnutrition. Therefore, a large number of affected children are not adequately diagnosed.
One aim of this study is to assess the prevalence of malnutrition and patients at risk for malnutrition among at least 2700 hospitalized children mainly across Europe. In addition criteria to link anthropometric measurements and the prediction of outcome, i.e. length of hospital stay, shall be established. A further goal then is to establish agreed, evidence-based criteria for malnutrition in children with the purpose of leading to an agreed, evidence-based screening tool for paediatric malnutrition in developed countries. This tool shall include a set of simple questions, based on previously suggested tools. Thereby this study will provide a strong basis for implementing evidence-based nutritional interventions in paediatric patients by harmonisation of diagnostic criteria for childhood malnutrition in developed countries.
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Notify Me1 month–18 year
All sexes
Observational
Children's Hospital Zagreb, Zagreb, Croatia
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: 60 days
Length of Hospital Stay will be compared between malnourished and non malnourished children.
Time frame: 60 days
frequency of infectious complications (number of days with temperature >38,5°C, number of days with days with antibiotic use)
Time frame: 60 days
frequency of gastrointestinal complications: frequency of vomiting and diarrhoea during hospital stay
Time frame: within 24 hours after admission
maximal isometric grip force in children ≥ 6 years of age measured within 24 hours after admission
Ludwig-Maximilians - University of Munich
Other
Malnutrition and Outcome in Hospitalized Children in Europe (ESPEN Network Grant Project)
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