Mail-in HPV Screening Program in NJ

Inclusion criteria

• Women, transgender men, and nonbinary individuals aged 30 to 75 who have a cervix.
• No history of hysterectomy or cervical cancer.
• No documented cervical cancer screening within guideline-recommended intervals: specifically, no Pap test in the past 3.5 years, no Pap/HPV co-test in the past 5.5 years, and no standalone HPV test results in the past 5.5 years. (A 6-month grace period is included to allow time for response to usual care outreach.)
• At least two visits to University Hospital ambulatory care over the past five years, ensuring opportunity for follow-up and continuity of care.

Exclusion criteria

• History of cervical dysplasia within the past 3.5 years, reflecting those likely under active surveillance or treatment protocols.
• Currently pregnant, due to differing screening recommendations and clinical considerations.
• Prior or current diagnosis of cervical cancer or ongoing treatment for cervical neoplasia.
• Physical, cognitive, or functional limitations that would preclude use of the mailed self-sampling kit without assistance. Examples include severe arthritis or significant impairment affecting self-collection capability.
• Lack of a telephone number or reliable mailing address on file.
• Inability to communicate in English or Spanish, given study materials and staffing capabilities. Use of additional language services is not available.
• Current enrollment in other cervical cancer screening or intervention studies that may interfere with participation or outcomes.
• Inability to provide informed consent or comprehend study procedures based on cognitive capacity, as assessed by the Research Coordinator during initial contact.