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Completed

NCT Number: NCT05289960

Lung Ultrasound Score and Weaning Outcome

Objectives: Failure of extubation of patients on mechanical ventilation is one of the common problems in the ICU.

Aim of work: To evaluate the validity of lung ultrasound score in prediction of weaning outcomes and post-extubation distress.

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Key information

Conditions

Lung Ultrasound Score Acute Respiratory Failure

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Cairo University Hospitals

Cairo, 11345, Egypt

About this study

Methods: A prospective observational study of 50 patients planned for extubation who passed a spontaneous breathing trial, lung ultrasound score and serum level of NT-PRO BNP were done to all patients at end of spontaneous breathing trial, and all patients were followed after extubation and monitored for oxygenation, re-intubation rate, ICU stay, and ICU mortality.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 1. Patients age > 18 years
  • Patients intubated and mechanically ventilated for more than 48 hours in the intensive care unit and planned for extubation.

Exclusion criteria

  • 1. Patients < or =18 years 2. Patients with left ventricular failure
  • Right ventricular failure
  • Pulmonary hypertension
  • Aortic valve disease
  • Hyperthyroidism
  • Tracheostomy

Treatment and study plan

Lung ultrasound

Other

Lung ultrasound score was done at the end of SBT using curved array ultrasound probe 2-5 MHz, Siemens X300, Korea

Primary outcomes

  1. Extubation success

    Time frame: 48 hours

    number of participants that do not need for respiratory support neither NIV nor intubation for one week during ICU stay

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Lung Ultrasound Score for Prediction of Weaning Outcome

Important dates

Study start
2020
Primary completion
2022
Study completion
2022
First posted
Mar 22, 2022
Registry last updated
Apr 1, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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