Saint Thomas Hospital
Panama City, Provincia de Panamá, Panama
Location status: Recruiting
NCT Number: NCT07261956
This research aims to evaluate the usefulness of lung ultrasound (LUS) for detecting and monitoring fluid overload in patients with severe preeclampsia. Severe preeclampsia is a leading cause of maternal death and illness worldwide, often causing fluid buildup that can lead to a serious complication called pulmonary edema, especially after delivery.
The study will be a prospective, longitudinal observational study with a diagnostic validation component. It will involve patients with a diagnosis of severe preeclampsia who meet specific inclusion criteria. Each participant will undergo a clinical exam and a lung ultrasound, which will assess eight zones of the lungs. The total number of B-lines-a sign of interstitial edema-will be documented.
Data will be collected at three key times: upon admission, in the immediate postpartum period (within 24 hours of delivery), and 7-10 days postpartum. The results from the LUS will be compared to clinical signs like shortness of breath, rapid breathing, crackling sounds in the lungs, and oxygen saturation levels.
The expected impact of this research is to provide evidence that LUS is a valuable, non-invasive, and accessible tool for the early detection of pulmonary congestion in patients with severe preeclampsia. This could lead to improved clinical decision-making and a reduction in maternal respiratory complications.
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Interventional
Not applicable
Panama City, Provincia de Panamá, Panama
Location status: Recruiting
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Lung ultrasounf at three moments (at admission, before delivery and immediate post partum) to determine B Lines
Time frame: One evaluation at admission, another one just before delivery and a final one 24 hours after delivery
Three or more B Lines in at least two lung zones using lung ultrasound
Time frame: Report of the symptom by the patient from admission for up to three days
Subjective sensation of difficulty breathing
Time frame: Report of the symptom from admission for up to three days.
Respiratory rate above 20 breaths/min
Time frame: Report of the value measured by a pulse oxymeter from admission for up to three days
Oxygen saturation measured by pulse oxymeter
Contact information is provided by the study sponsor or research team.
Adriana Martinz, MD
CONTACT
Anna C Figueroa, MD
CONTACT
Saint Thomas Hospital, Panama
Other
Usefulness of Lung Ultrasound for the Detection of Volume Overload in Patients With Severe Preeclampsia
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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