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Completed

NCT Number: NCT01881061

Lung Sonography in Patients With Acute Respiratory Distress Syndrome in Intensive Care Unit

The purpose of this study is to evaluate the role of lung sonography during different PEEP settings in ICU patients with ARDS.

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Key information

Conditions

ARDS

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

First Critical Care Unit, Evaggelismos Hospital, School of Medicine, University of Athens

Athens, Attica, 10676, Greece

About this study

Acute respiratory distress syndrome (ARDS) is a clinical syndrome that often occurs in critically ill patients.

Patients with ARDS invariably require mechanical ventilation to improve oxygen transport. An improvement in oxygenation can be obtained by an increase in positive end-expiratory pressure (PEEP).

In critically ill patients with ARDS, lung imaging is been held by the use of chest radiography and the "gold standard" technique, Computed Tomography (CT).

We designed an observational study in which we included patients under mechanical ventilation admitted in our ICU. In all patients PEEP changes were applied and lung sonography was performed.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Critically ill patients with ARDS admitted in ICU of Evangelismos Hospital
  • length of stay > 48 hours

Exclusion criteria

  • age < 18 years
  • emphysema fractures or skin lesions that do not allow the implementation of lung sonography
  • BMI > 35 kg/m2
  • length of stay < 48 hours

Treatment and study plan

Primary outcomes

  1. Non aerated lung area changes

    Time frame: 20 min after PEEP trial

Secondary outcomes

  1. Arterial oxygen and carbon dioxide partial pressure

    Time frame: 20 min after PEEP trial

Sponsors and collaborators

Lead sponsor

University of Athens

Other

Registry information

Important dates

Study start
2009
Primary completion
2011
Study completion
2011
First posted
Jun 19, 2013
Registry last updated
Jun 19, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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