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OpenTrials
Active, Not Recruiting

NCT Number: NCT06879535

Long-term Symptomatic Follow-up of Patients with Long COVID Syndrome

The goal of this observational study is to learn about the long-term evolution of long COVID.

The main question it aims to answer is:

Does the main symptoms of the patients diagnosed with long COVID aproximate to those of patients who have had COVID acute infection without devoloping long COVID? Participants will answer mailed survey questions about their main symptons.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Long COVID COVID-19 Chronic Disease Coronaviridae Infections Coronavirus Infections Disease Attributes Infections Lung Diseases Nidovirales Infections Pathologic Processes Pathological Conditions, Signs and Symptoms Pneumonia Pneumonia, Viral Post-Acute COVID-19 Syndrome Post-Infectious Disorders RNA Virus Infections Respiratory Tract Diseases Respiratory Tract Infections Virus Diseases

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Hospital Universitario Río Hortega

Valladolid, 47012, Spain

About this study

Scales, indexes and questionnaires were mailed to 40 patients with long COVID to evaluate their main symptoms. Fatigue, emotional disorders, sleep disorders, cognitive impairments, dyspnea, physical activity, quality of life and pain were analyzed. The patients were reassessed after three years. The same scales, indexes and questionnaires were also sent to a control group of 40 volunteers of the same age and sex as the cases.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients older than 18 years old and younger than 75 years old
  • patients who accepted to participate in the study
  • patients who have had COVID acute infection
  • patients who have long COVID (cases)

Exclusion criteria

  • patients who refused to participate in the study at any time of the study
  • patients whose diagnosis of long COVID was revoked during the study (cases)

Treatment and study plan

Primary outcomes

  1. Fatigue

    Time frame: From enrollment to three years later

    MFIS scale

  2. Emotional disorders

    Time frame: From enrollment to three years later

    HADS scale

  3. Sleep disorders

    Time frame: From enrollment to three years later

    PSQI

  4. Cognitive impairments

    Time frame: From enrollment to three years later

    MFE-30

  5. Dyspnea

    Time frame: From enrollment to three years later

    mMRC

  6. Physical activity

    Time frame: From enrollment to three years later

    GPAQ

  7. Quality of life (healthcare)

    Time frame: From enrollment to three years later

    SF-36

  8. Pain (healthcare)

    Time frame: From enrollment to three years later

    EGDC

Sponsors and collaborators

Lead sponsor

Hospital del Rio Hortega

Other

Registry information

Official study title

ESTUDIO DE APLICACIÓN DE ESCALAS PARA VALORACIÓN SINTOMÁTICA DEL SÍNDROME DE COVID PERSISTENTE

Important dates

Study start
2022
Primary completion
2025
Study completion
2025
First posted
Mar 17, 2025
Registry last updated
Mar 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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