Long-Term Follow Up of VOY-101 Non-nAMD Extension Study

Long-Term Follow Up Extension for participants previously enrolled in a VOY-101 study for Advanced Non-Neovascular Age-Related Macular Degeneration

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Key information

Conditions

Age-related Macular Degeneration (AMD) Eye Diseases Macular Degeneration Non-Neovascular Age-Related Macular Degeneration Retinal Degeneration Retinal Diseases

Age range

50 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Sourasky Medical Center - Ichilov, Tel Aviv, Israel

About this study

This is a long-term observational, non-interventional extension study to the Phase 1/2a studies that administered VOY-101 to subjects with advanced non-neovascular age-related macular degeneration (AMD).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Have received an injection of VOY-101 and exited either the PBI-AMD-001 or PBI-AMD-002 Phase 1/2a study of VOY-101.
Are willing and able to understand and provide informed consent.

Exclusion criteria

There are no exclusion criteria for this study

Treatment and study plan

observational study

Other

No intervention - observational study

VOY-101

Biological

One-time intravitreal injection of VOY-101.

Primary outcomes

Frequency of ocular and systemic VOY-101 related AEs

Time frame: 3 years

Frequency of ocular and systemic VOY-101 related AEs (serious [SAEs] and treatment-emergent non-serious adverse events [TEAEs]).

Sponsors and collaborators

Lead sponsor

Perceive Biotherapeutics, Inc.

Industry

Registry information

Official study title

Long-Term Follow Up of VOY-101 for Advanced Non-Neovascular Age-Related Macular Degeneration Extension Study

Acronym: OASIS

Important dates

Study start: 2026
Primary completion: 2031
Study completion: 2031
First posted: Jun 22, 2026
Registry last updated: Jun 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Enrolling by Invitation