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NCT Number: NCT06884644

Local and Systemic Oxygen Saturation During 'Death by Squats' Exercise

During the exercise intervention "Death by Squats", which compasses body weight squats until maximum exertion, 25-30 subjects shall be tested for heart rate, the oxygen saturation of the vastus medialis and the triceps, resting and at maximum exertion blood lactate, as well as the rate of perceived exertion on the borg scale. At the end, all should indicate their primary reason for stopping (local fatigue, systemic fatigue, time constraints, motivational deficit).

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University of the Bundeswehr Munich

Munich, Bavaria, 85577, Germany

Location status: Recruiting

Location contact

Petra Neudorfer

CONTACT

[email protected]

+49 89 6004 4181

About this study

Subjects in this study will be measured while they are engaged in an exercise protocol until maximum exertion, each in groups of three persons. The overall duration of the study is planned from April 2023 (start of recruitment) until December 2024 (finalization of data acquisition and analysis).

Subjects are executing a CrossFit workout which is planned as follows: Every minute, participants have to perform a given number of Airsquats (bodyweight squat). The first minute starts off with 10 repetitions, the remaining time can be used as a break. In minute two, 12 repetitions have to be done, in minute three 14 repetition, and so on. The subjects stick to this protocol until maximum exertion, in other words, until they are no longer able to execute the given repetitions within the actual minute. During the workout, heart rate is tracked by a 'Polar' chest strap, and the oxygen saturation of the vastus medialis and the triceps are measured using the 'Moxy' muscle oxygen monitor. Further, at rest and at maximum exertion, a blood lactate sample is taken (EKF lactate scout). Subjects rate their perceived exertion on the borg scale after quitting and indicate their primary reason for stopping (local fatigue in legs, systemic fatigue, time constraints).

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • being moderately to severely physically active al least 2 hours/week (all types of sport are eligible)

Exclusion criteria

  • akute infections, musculoskeletal injuries
  • chronic cardiovascular or pulmonary diseases (in case of uncertainty, we recommend appraisal from medical personnel)

Treatment and study plan

Death by Airsquat

Diagnostic Test

Increasing number of squats have to be completed every minute (EMOM principle).

Primary outcomes

  1. Local and systemic SmO2 curve

    Time frame: From the start of the exercise intervention until individual exhaustion (expected between 15 to 30 minutes), with SmO₂ continuously recorded during exercise and final measurement taken immediately upon exhaustion.

Secondary outcomes

  1. Type of sports practiced

    Time frame: Questionnaire administered within 5 minutes after test completion to assess type of sports practiced.

Other outcomes

  1. Anthropometric parameters will be assessed

    Time frame: Anthropometric measurements will be taken immediately after the completion of the exercise intervention (expected between 15 to 30 minutes after the start of exercise).

    The following anthropometric parameters will be assessed:

    • body mass (kg)
    • body height (cm)
    • BMI (kg/m², calculated from body mass and height)
    • limb circumference (cm)
    • skinfold thickness (mm)
  2. Blood lactate concentration at rest and post-exercise

    Time frame: At rest (prior to exercise) and immediately upon individual exhaustion (expected between 15 to 30 minutes after the start of exercise). Additional post-exercise measurements at 2, 5, and 10 minutes if applicable.

Study contacts

Contact information is provided by the study sponsor or research team.

Annette Schmidt, Prof

CONTACT

[email protected]

+49 89 6004 4412

Jennifer Schlie, M.Sc.

CONTACT

[email protected]

+49 89 6004 4774

Sponsors and collaborators

Lead sponsor

Bundeswehr University Munich

Other

Registry information

Official study title

Analysis of Local and Systemic Oxygen Saturation During Monotonous Exercise Using the Example of 'Death by Squats'

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Mar 19, 2025
Registry last updated
Mar 19, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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