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Completed

NCT Number: NCT06101628

Effect of Gel Nail Application on Pulse Oximetry Measurements in Healthy Individuals

The aim of this study was to determine the effect of gel nail application on pulse oximetry measurements in healthy subjects. This study was planned as a prospective, self-controlled clinical research to determine the effect of gel nail application on SpO2 and pulse values in healthy people. The population of the study will consist of women who had gel nail application in a private beauty centre between July 2023 and July 2024. The minimum required sample size was calculated as 162 in G*Power (3.1.9.2) programme (α=0.05 (two-way), 1-β=0.95). The data will be collected with the data collection form prepared in line with the literature.First, the age and smoking status of participants who meet the research criteria will be recorded on the data collection form. Then, the finger to which the gel nail polish will be applied and the control finger will be determined by drawing lots between the index fingers. Based on the result of this draw, gel nail polish will be applied to the left index finger of each participant, while the right index finger will be used as the control. Following the application of gel nail polish, SpO₂ and heart rate (HR) measurements will be obtained simultaneously from the left and right index fingers using pulse oximeters (POs). All measurements will be performed under standardized conditions: (1) participants will rest for at least 5 minutes before measurements, (2) their hands will be positioned at heart level, (3) ambient lighting and room temperature will be kept constant, and (4) participants will be instructed to remain still during measurements. These procedures will be applied consistently to all participants in order to minimize variability and enhance data reliability. The data obtained from the study will be analysed using SPSS (Statistical Package for Social Sciences) for Windows 26.0 software.

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Key information

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Gamze Bozkul

Mersin, Turkey, 33400, Turkey (Türkiye)

About this study

The aim of this study was to determine the effect of gel nail application on pulse oximetry measurements in healthy subjects. This study was planned as a prospective, self-controlled clinical research to determine the effect of gel nail application on SpO2 and pulse values in healthy people. The population of the study will consist of women who had gel nail application in a private beauty centre between July 2023 and July 2024. The minimum required sample size was calculated as 162 in G*Power (3.1.9.2) programme (α=0.05 (two-way), 1-β=0.95). The data will be collected with the data collection form prepared in line with the literature.On this form, the age of the individual, the color of the gel nail, smoking status, and the SpO2 and pulse values measured by pulse oximetry. First, the age and smoking status of participants who meet the research criteria will be recorded on the data collection form. Then, the finger to which the gel nail polish will be applied and the control finger will be determined by drawing lots between the index fingers. Based on the result of this draw, gel nail polish will be applied to the left index finger of each participant, while the right index finger will be used as the control. Following the application of gel nail polish, SpO₂ and heart rate (HR) measurements will be obtained simultaneously from the left and right index fingers using pulse oximeters (POs).

All measurements will be performed under standardized conditions: (1) participants will rest for at least 5 minutes before measurements, (2) their hands will be positioned at heart level, (3) ambient lighting and room temperature will be kept constant, and (4) participants will be instructed to remain still during measurements. These procedures will be applied consistently to all participants in order to minimize variability and enhance data reliability. The data obtained from the study will be analysed using SPSS (Statistical Package for Social Sciences) for Windows 26.0 software. Mean and standard deviation will be used in the evaluation of the data. Statistical significance will be accepted as p<0.05 (95% confidence interval).

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • No communication problems,
  • With full left-hand fingernails,
  • No structural problems such as clubbing,
  • Body temperature ≥ 36- <37.5 ºc,
  • SpO2 value ≥ 95%,
  • Capillary refill ≤ 2 seconds,
  • Who volunteered to participate in the research,
  • No psychiatric or physical illness that prevents communication,
  • Without circulatory problems such as Reynauld syndrome and peripheral arterial disease,
  • Without anaemia,
  • No respiratory diseases such as chronic obstructive pulmonary disease and asthma
  • Becoming a woman

Exclusion criteria

  • Communication problems,
  • Incomplete left fingernails,
  • Structural problems like sticky fingers,
  • Body temperature ≥ 36- < 37.5 ºc,
  • SpO2 value <95%,
  • Capillary refill >2 seconds,
  • Not volunteering to participate in the research,
  • Psychiatric or physical illness that prevents communication,
  • With circulatory problems such as Reynauld syndrome and peripheral arterial disease,
  • Anaemia
  • Respiratory diseases such as chronic obstructive pulmonary disease and asthma
  • Not being of the female gender

Treatment and study plan

Gel nail application

Other

The finger to which the gel nail polish will be applied and the control finger will be determined by drawing lots between the index fingers. Based on the result of this draw, gel nail polish will be applied to the left index finger of each participant, while the right index finger will be used as the control. Following the application of gel nail polish, SpO₂ and heart rate (HR) measurements will be obtained simultaneously from the left and right index fingers using pulse oximeters (POs).

Other names: Control group: Non-applied nail

Primary outcomes

  1. SpO2 value

    Time frame: 3 months

    Data collection form: Following the application of gel nail polish, SpO₂ measurements will be obtained simultaneously from the left and right index fingers using pulse oximeters (POs).

  2. Pulse value

    Time frame: 3 months

    Data collection form: Following the application of gel nail polish, heart rate (HR) measurements will be obtained simultaneously from the left and right index fingers using pulse oximeters (POs).

Sponsors and collaborators

Lead sponsor

Tarsus University

Other

Collaborators

  • Mersin University
  • Mustafa Kemal University
  • Necmettin Erbakan University

Registry information

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Oct 26, 2023
Registry last updated
Jun 10, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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