Skip to main content
OpenTrials
Completed

NCT Number: NCT02124382

Living Donor Liver Transplantation in Children

Evaluate the outcome of pediatric living donor liver transplantation (LDLT) regarding portal vein reconstruction, ABO-compatibility and impact of maternal donation on graft acceptance.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Pediatric Liver Transplanted Recipients Digestive System Diseases Healthy Donors Hepatic Insufficiency Liver Diseases Liver Failure Metabolic Diseases Nutritional and Metabolic Diseases

Age range

Up to 57 year

Sex eligibility

All sexes

Study type

Observational

About this study

Data from 250 pediatric LDLT recipients (and their donors), transplanted at Cliniques universitaires Saint-Luc between July 1993 and June 2012, were collected retrospectively using electronic data files. Results were analysed according to ABO matching and portal vein complications. Uni- and multi-variate analysis was used to study the impact of immunosuppression, gender match and maternal donation on acute rejection rate.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Children receiving a living donor liver transplant
  • Adult living donors

Exclusion criteria

  • No one

Treatment and study plan

Primary outcomes

  1. Patient and graft survival

    Time frame: 10 years

    Kaplan-Meier

Secondary outcomes

  1. Portal vein complications

    Time frame: 10 years

Other outcomes

  1. Graft rejection free survival

    Time frame: 10 years

Sponsors and collaborators

Lead sponsor

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Other

Registry information

Official study title

Living Donor Liver Transplantation in Children: Surgical and Immunological Results in 250 Recipients at Université Catholique de Louvain.

Important dates

Study start
2012
Primary completion
2014
Study completion
2014
First posted
Apr 28, 2014
Registry last updated
Apr 28, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.