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Completed

NCT Number: NCT02448745

Liberia Insecticide Treated Durable Wall Linings Study: Protocol for a Cluster Randomised Trial (DL)

A cluster-randomized control trial will study the effect of insecticide-treated wall lining on malaria transmission in Bomi County, Liberia. Half of the villages enrolled in the study will receive insecticide-treated wall lining covering their walls and ceilings in addition to long-lasting insecticidal nets, while the other half will be protected by existing long-lasting insecticidal nets.

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Key information

Conditions

Malaria, Falciparum Anemia Hematologic Diseases Hemic and Lymphatic Diseases Infections Malaria Mosquito-Borne Diseases Parasitic Diseases Protozoan Infections Vector Borne Diseases

Age range

2 month–59 month

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Bomi County Health Team

Tubmanburg, Bomi County, Liberia

About this study

Long-lasting insecticidal nets (LLINs) are the established vector control product for malaria control. In Bomi County Liberia, LLINs have been distributed but malaria prevalence in children under 5 remains high, with prevalence in study villages found to be 42% in April 2014. The major malaria vector species are resistant to pyrethroid insecticides approved for use in LLINs, and new control measures with non-pyrethroid active ingredients may protect the population.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Child resides in village
  • Child presents with parent or guardian

Exclusion criteria

  • Child or guardian has history of Ebola exposure
  • Child has 3 symptoms of Ebola

Treatment and study plan

Insecticide treated wall lining

Device

Polypropylene non-woven fabric.

Other names: Durable wall lining, PermaNet Lining

Primary outcomes

  1. Malaria Prevalence

    Time frame: 6 months

    Tested by mRDT and PCR

Secondary outcomes

  1. Hemoglobin

    Time frame: 6 months

    Hemoglobin measured by Hemocue 301

  2. Fever

    Time frame: 6 months

    Number of participants with Fever, defined as tympanic temperature above 37.5C

  3. Mosquito biting rate.

    Time frame: 2 months

    Mosquitoes trapped indoors and outdoors using light traps and exit traps.

Sponsors and collaborators

Lead sponsor

The Mentor Initiative

Other

Collaborators

  • Ministry of Health, Liberia

Registry information

Important dates

Study start
2014
Primary completion
2016
Study completion
2017
First posted
May 19, 2015
Registry last updated
May 1, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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