Lead Mobilization & Bone Turnover in Pregnancy/Lactation

We are examining the role of maternal bone lead turnover during pregnancy and lactation as a potential source of lead exposure for the fetus and the infant (via breast milk). A cohort, ascertained at entry to care, consists of >1000 women to be followed through pregnancy. In the postpartum subjects are recruited for a nested case control study to assess the influence of lactation on maternal bone density, maternal blood lead and breast milk lead.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Lead Poisoning Behavior Breast Feeding Chemically-Induced Disorders Feeding Behavior Heavy Metal Poisoning Poisoning

Age range

12 year–35 year

Sex eligibility

Female

Study type

Observational

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Positive pregnancy test, age 12-35 and informed consent;
Gestation <28 weeks at entry to prenatal care;
No history of serious chronic or metabolic diseases, which could affect maternal growth or bone density;
Not corticosteroid user or diagnosed use of illicit drugs;
Eligible for lactation study: Ascertainment during or participation in the pregnancy study and a negative pregnancy test.

Sponsors and collaborators

Lead sponsor

National Institute of Environmental Health Sciences (NIEHS)

Nih

Registry information

Important dates

Study start: 1996
Study completion: 2002
First posted: Mar 1, 2001
Registry last updated: Mar 23, 2006

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed