Large Cohort of 1000 Patients With Severe Myopia

This study allows to describe the evolution of different ophthalmological parameters of a population of strong myopes during their follow-up for 10 years using multimodal imaging techniques of the retina.

Prospective, longitudinal, multicentric, non-randomized cohort study with constitution of a biological collection.

This study will include major and minor patients with high myopia

Inclusion criteria

• Age ≥ 6 years
• Severe myopia in at least one eye, defined as

• a refractive error ≤ -6.00 diopters OR
• an axial length ≥ 26.50 mm
• Follow-up performed at at least one of the participating centers
• Express consent to participate in the study
• If age < 18 years: express consent of the person(s) exercising parental authority
• Affiliated or beneficiary of a health insurance

Exclusion criteria

• Visual acuity < 5 letters on the ETDRS (equivalent to "finger count" or less) in both eyes
• Disorders of the transparent media in both eyes with opacities that may affect image quality
• Syndromic myopia of genetic origin (Stickler syndrome type 1 and 2, Marfan syndrome, Ehler-Danlos disease type 4, Knobloch syndrome) or inherited retinal dystrophy (X-linked retinitis pigmentosa, congenital stationary night blindness of Schubert-Bornshein type, Bornholm eye disease)
• Patient who does not wish to continue to be followed in one of the participating centers
• Patient benefiting from a legal protection measure
• Pregnant or breastfeeding woman