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Active, Not Recruiting

NCT Number: NCT04700111

Lag of Accommodation With DOT Spectacle Lenses

The objective of the study is to measure the difference in the lag of accommodation between DOT spectacle lenses and control spectacles.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Age range

6 year–18 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Centre for Ocular Research and Education

Waterloo, Ontario, N2L 3G1, Canada

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

A person is eligible for inclusion in the study if he/she:

  • Age 6-18 years of age, with a maximum of 6 of the first 25 completed participants being older than 14 years of age.
  • Is able to read (or be read to), understand and sign the assent document if under 17 years old or is able to read, understand and sign the consent document if aged 17 or 18 years.
  • Is under 17 years old and is accompanied by a parent or legal guardian who is able to read, understand and sign the parental information and permission document.
  • Should be emmetropic by non-cycloplegic auto-refraction, which means both refractive meridians should be within +1.00D and -1.00D.
  • Is willing and able to follow instructions.

A person will be excluded from the study if he/she:

  • Is participating in any concurrent clinical or research study.
  • Have a history of myopia control treatment in the past year.
  • Has amblyopia in either eye or known to have any other binocular vision disorder, such as accommodative insufficiency.
  • Has any known active ocular disease and/or infection.
  • Has a systemic condition that in the opinion of the investigator may affect a study outcome variable. Examples include diabetes mellitus, hyperthyroidism.
  • Is using any systemic or topical medications that in the opinion of the investigator may affect a study outcome variable. Examples include Atropine eye drops.
  • Has undergone strabismus surgery, refractive error surgery or intraocular surgery.
  • Is a child of a member of the study team.

Treatment and study plan

DOT Pattern

Device

DOT Pattern Spectacle Lens

Control Spectacles

Device

Control lens

Primary outcomes

  1. Best vision sphere

    Time frame: 90 minutes

    • Autorefractor spherical equivalent refraction measured at distance and at 40cm with each pair of treatment spectacles

Sponsors and collaborators

Lead sponsor

SightGlass Vision, Inc.

Industry

Collaborators

  • University of Waterloo

Registry information

Acronym: ASH

Important dates

Study start
2022
Primary completion
2022
Study completion
2026
First posted
Jan 7, 2021
Registry last updated
May 5, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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